Calix[4]arene N-chalconeamides:: synthesis and influence on Mg2+,ATP-dependent Ca2+ accumulation in the smooth muscle subcellular structures

被引:14
作者
Klyachina, Mariia A. [1 ]
Boyko, Vyacheslav I. [1 ]
Yakovenko, Anton V. [1 ]
Babich, Lidiya G. [2 ]
Shlykov, Sergiy G. [2 ]
Kosterin, Sergiy O. [2 ]
Khilya, Volodymyr P. [3 ]
Kalchenko, Vitaly I. [1 ]
机构
[1] Natl Acad Sci Ukraine, Inst Organ Chem, UA-02660 Kiev, Ukraine
[2] Natl Acad Sci Ukraine, AV Palladin Biochem Inst, UA-01601 Kiev, Ukraine
[3] Kyiv Taras Shevchenko Natl Univ, UA-01033 Kiev, Ukraine
关键词
calix[4]arene; chalcone; Ca2+ accumulation; smooth muscle subcellular structure;
D O I
10.1007/s10847-007-9361-9
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The cone-shaped calixarene N-chalconeamides were synthesized by the reaction of calix[4]arene carboxylic acids or acid chlorides with aminochalcones. It was found, that calixarene chalconeamides influence the Mg2+, ATP-dependent Ca2+ accumulation in mitochondria and sarcoplasmatic reticulum of the smooth muscle cells.
引用
收藏
页码:131 / 137
页数:7
相关论文
共 35 条
  • [1] Modulation of cation binding in calix[4]arene amides: synthesis, complexation and molecular modelling studies
    Arnaud-Neu, MF
    Barboso, S
    Berny, F
    Casnati, A
    Muzet, N
    Pinalli, A
    Ungaro, R
    Schwing-Weill, MJ
    Wipff, G
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1999, (08): : 1727 - 1738
  • [2] SELECTIVE ALKALI-METAL CATION COMPLEXATION BY CHEMICALLY MODIFIED CALIXARENES .4. EFFECT OF SUBSTITUENT VARIATION ON THE NA+/K+ SELECTIVITY IN THE ESTER SERIES AND X-RAY CRYSTAL-STRUCTURE OF THE TRIFLUOROETHYL ESTER
    ARNAUDNEU, F
    BARRETT, G
    CREMIN, S
    DEASY, M
    FERGUSON, G
    HARRIS, SJ
    LOUGH, AJ
    GUERRA, L
    MCKERVEY, MA
    SCHWINGWEILL, MJ
    SCHWINTE, P
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1992, (07): : 1119 - 1125
  • [3] Babich L. G., 1994, Biokhimiya, V59, P1218
  • [4] Calix[4]arenes with CMPO functions at the narrow-rim.: Synthesis and extraction properties
    Barboso, S
    Carrera, AG
    Matthews, SE
    Arnaud-Neu, F
    Böhmer, V
    Dozol, JF
    Rouquette, H
    Schwing-Weill, MJ
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1999, (04): : 719 - 723
  • [5] CALIXARENES, MACROCYCLES WITH (ALMOST) UNLIMITED POSSIBILITIES
    BOHMER, V
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (07): : 713 - 745
  • [6] Peptido- and glycocalixarenes: Playing with hydrogen bonds around hydrophobic cavities
    Casnati, A
    Sansone, F
    Ungaro, R
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 2003, 36 (04) : 246 - 254
  • [7] Casnati A, 2001, CALIXARENES 2001, P365
  • [8] Calix[4]arene α-aminophosphonic acids:: Asymmetric synthesis and enantioselective inhibition of an alkaline phosphatase
    Cherenok, S
    Vovk, A
    Muravyova, I
    Shivanyuk, A
    Kukhar, V
    Lipkowski, J
    Kalchenko, V
    [J]. ORGANIC LETTERS, 2006, 8 (04) : 549 - 552
  • [9] Bioharmaceutical applications of calixarenes
    Da Silva, E
    Lazar, AN
    Coleman, AW
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2004, 14 (01) : 3 - 20
  • [10] CHALCONES AND RELATED COMPOUNDS .1. PREPARATION OF NITRO-CHALCONES, AMINO-CHALCONES, AND HALOGENO-CHALCONES
    DAVEY, W
    GWILT, JR
    [J]. JOURNAL OF THE CHEMICAL SOCIETY, 1957, (MAR): : 1008 - 1014