Preparation and characterization of strontium-containing HAP sol and studies on its effects on cancer and normal cells

Saturated calcium hydroxide solution and monocalcium phosphate were used as initial materials for hydroxyapatite preparation. The strontium hydroxide was used as strontium nitrition. The initial materials were prepared for nano strontium-containing hydroxyapatite sol. Nano strontium-containing hydroxyapatite particles were characterized. They are sized in scope of 20 run to 60 nm. The particles were analyzed by XRD and TEM, which verified the particles were strontium-containing apatite. The sol was applied to interact with Bel-7402 cells and L-02 cells. Experimental results revealed that nano strontium-containing hydroxyapatite has different bioeffects on cell line Bel-7402 and L-02.