Appetite for Arginine: Metabolic Control of Macrophage Hunger

被引:4
|
作者
Puleston, Daniel J. [1 ,2 ]
Pearce, Erika L. [1 ]
机构
[1] Max Planck Inst Immunobiol & Epigenet, D-79108 Freiburg, Germany
[2] Univ Oxford, Kennedy Inst Rheumatol, Oxford OX3 7FY, England
基金
英国惠康基金;
关键词
CLEARANCE;
D O I
10.1016/j.cmet.2020.02.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.
引用
收藏
页码:441 / 442
页数:2
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