Nonhuman primate model in mammary gland biology and neoplasia research

被引：12
作者：
Dewi, Fitriya N. [1 ]
Cline, J. Mark [2 ]
机构：
[1] IPB Univ, Primate Res Ctr, Jl Lodaya II 5, Bogor 16151, West Java, Indonesia
[2] Wake Forest Univ, Bowman Gray Sch Med, Sect Comparat Med, Dept Pathol, Med Ctr Blvd, Winston Salem, NC 27157 USA
来源：
LABORATORY ANIMAL RESEARCH | 2021年 / 37卷 / 01期
关键词：
Breast cancer; Macaques; Monkey; Breast differentiation; Animal model; BREAST-CANCER RISK; DIETARY SOY; MEDROXYPROGESTERONE ACETATE; ENVIRONMENTAL ENRICHMENT; CYNOMOLGUS MONKEYS; PROGESTERONE; TAMOXIFEN; ESTRADIOL; HORMONE; MOUSE;
D O I：
10.1186/s42826-020-00053-1
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Research on breast cancer pathogenesis, prevention and drug development remains an important field as this disease is still one of the leading causes of cancer death worldwide. Nonhuman primates, particularly macaque species, may serve as a highly translational animal model in breast cancer studies due to their similarity with humans in genetics, anatomy, reproductive and endocrine physiology including mammary gland development profile. The use of nonhuman primates in biomedical research, however, requires high ethical standards and an increasing expectation to improve strategies to replace, reduce and refine their use. Here, we discuss some key features of nonhuman primate mammary gland biology relevant to their strengths and limitations as models in studies of breast development and cancer risk.
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页数：10
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共 83 条
  • [1] Breast cancer risk by age at birth, time since birth and time intervals between births:: exploring interaction effects
    Albrektsen, G
    Heuch, I
    Hansen, S
    Kvåle, G
    [J]. BRITISH JOURNAL OF CANCER, 2005, 92 (01) : 167 - 175
  • [2] Serum antimullerian hormone predicts ovarian reserve in a monkey model
    Appt, Susan E.
    Clarkson, Thomas B.
    Chen, Haiying
    Adams, Michael R.
    Christian, Patricia J.
    Hoyer, Patricia B.
    Wilson, Mark E.
    Kaplan, Jay R.
    [J]. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2009, 16 (03): : 597 - 601
  • [3] Lobule Type and Subsequent Breast Cancer Risk: Results From the Nurses' Health Studies
    Baer, Heather J.
    Collins, Laura C.
    Connolly, James L.
    Colditz, Graham A.
    Schnitt, Stuart J.
    Tamimi, Rulla M.
    [J]. CANCER, 2009, 115 (07) : 1404 - 1411
  • [4] Characterization of human-like menstruation in the spiny mouse: comparative studies with the human and induced mouse model
    Bellofiore, Nadia
    Rana, Shreya
    Dickinson, Hayley
    Temple-Smith, Peter
    Evans, Jemma
    [J]. HUMAN REPRODUCTION, 2018, 33 (09) : 1715 - 1726
  • [5] Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies
    Beral, V.
    Bull, D.
    Pirie, K.
    Reeves, G.
    Peto, R.
    Skegg, D.
    LaVecchia, C.
    Magnusson, C.
    Pike, M. C.
    Thomas, D.
    Hamajima, N.
    Hirose, K.
    Tajima, K.
    Rohan, T.
    Friedenreich, C. M.
    Calle, E. E.
    Gapstur, S. M.
    Patel, A. V.
    Coates, R. J.
    Liff, J. M.
    Talamini, R.
    Chantarakul, N.
    Koetsawang, S.
    Rachawat, D.
    Marcou, Y.
    Kakouri, E.
    Duffy, S. W.
    Morabia, A.
    Schuman, L.
    Stewart, W.
    Szklo, M.
    Coogan, P. F.
    Palmer, J. R.
    Rosenberg, L.
    Band, P.
    Coldman, A. J.
    Gallagher, R. P.
    Hislop, T. G.
    Yang, P.
    Cummings, S. R.
    Canfell, K.
    Sitas, F.
    Chao, P.
    Lissowska, J.
    Horn-Ross, P. L.
    John, E. M.
    Kolonel, L. M.
    Nomura, A. M. Y.
    Ghiasvand, R.
    Hu, J.
    [J]. LANCET ONCOLOGY, 2012, 13 (11) : 1141 - 1151
  • [6] Binder AM, 2018, CANCER EPIDEM BIOMAR, V27, P1491, DOI [10.1158/1055-9965.epi-17-0813, 10.1158/1055-9965.EPI-17-0813]
  • [7] BLOOMSMITH MA, 1991, LAB ANIM SCI, V41, P372
  • [8] Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study
    Bodicoat, Danielle H.
    Schoemaker, Minouk J.
    Jones, Michael E.
    McFadden, Emily
    Griffin, James
    Ashworth, Alan
    Swerdlow, Anthony J.
    [J]. BREAST CANCER RESEARCH, 2014, 16 (01):
  • [9] Choosing a Mouse Model: Experimental Biology in Context - The Utility and Limitations of Mouse Models of Breast Cancer
    Borowsky, Alexander D.
    [J]. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2011, 3 (09): : 1 - 16
  • [10] Influence of estrogen plus progestin on breast, cancer and mammography in healthy postmenopausal women - The Women's Health Initiative Randomized trial
    Chlebowski, RT
    Hendrix, SL
    Langer, RD
    Stefanick, ML
    Gass, M
    Lane, D
    Rodabough, RJ
    Gilligan, MA
    Cyr, MG
    Thomson, CA
    Khandekar, J
    Petrovitch, H
    McTiernan, A
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (24): : 3243 - 3253
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