RIZ1, a protein/histone methyltransferase superfamily member, is epigenetically silenced in human AML and its constitutive expression promotes apoptosis and differentiation.

被引:0
|
作者
Dong, WF [1 ]
Scott, SA [1 ]
Guo, Y [1 ]
Bergen, SP [1 ]
Sheridan, DP [1 ]
DeCoteau, JF [1 ]
机构
[1] Univ Saskatchewan, Saskatoon, SK S7N 0W0, Canada
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2134
引用
收藏
页码:579A / 580A
页数:2
相关论文
共 4 条
  • [1] Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
    Du, Y
    Carling, T
    Fang, W
    Piao, Z
    Shen, JC
    Huang, S
    CANCER RESEARCH, 2001, 61 (22) : 8094 - 8099
  • [2] Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily
    Steele-Perkins, G
    Fang, W
    Yang, XH
    Van Gele, M
    Carling, T
    Gu, J
    Buyse, IM
    Fletcher, JA
    Liu, JS
    Bronson, R
    Chadwick, RB
    de la Chapelle, A
    Zhang, XK
    Speleman, F
    Huang, S
    GENES & DEVELOPMENT, 2001, 15 (17) : 2250 - 2262
  • [3] Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells
    M I Klisovic
    E A Maghraby
    M R Parthun
    M Guimond
    A R Sklenar
    S P Whitman
    K K Chan
    T Murphy
    J Anon
    K J Archer
    L J Rush
    C Plass
    M R Grever
    J C Byrd
    G Marcucci
    Leukemia, 2003, 17 : 350 - 358
  • [4] Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells
    Klisovic, MI
    Maghraby, EA
    Parthun, MR
    Guimond, M
    Sklenar, AR
    Whitman, SP
    Chan, KK
    Murphy, T
    Anon, J
    Archer, KJ
    Rush, LJ
    Plass, C
    Grever, MR
    Byrd, JC
    Marcucci, G
    LEUKEMIA, 2003, 17 (02) : 350 - 358