Two New Anthraquinone Glycosides from Gladiolus segetum

被引：9

作者：

Abdessemed, Dalila ^{[1
]}

Fontanay, Stephane ^{[2
]}

Duval, Raphael E. ^{[2
]}

Mattar, Dominique L. ^{[2
]}

Dibi, Ammar ^{[1
]}

机构：

[1] Univ Hadj Lakhdar, Fac Sci, Dept Chim, LCCE, Batna 05000, Algeria

[2] Nancy Univ, SRSMC, CNRS, UMR 7565, F-54506 Vandoeuvre Les Nancy, France

来源：

ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING | 2011年 / 36卷 / 01期

关键词：

Gladiolus segetum; Iridaceae; Anthraquinone glycosides; Cytotoxicity;

D O I：

10.1007/s13369-010-0015-7

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Two new anthraquinone glycosides: methyl 8-hydroxy-4,7-dimethoxy-1-methyl-9,10-dioxo-3-( beta-D-glucopyranosyloxy)-9,10-dihydroanthracene-2-carboxylate (1) and methyl 3-methoxy-1-methyl-9, 10-dioxo-8-(beta-D-glucopyranosyloxy)-9,10-dihydroanthracene-2-carboxylate (2), have been isolated from the methanolic extract of Gladiolus segetum. Their structures were established based on spectroscopic analyses. The fraction containing anthraquinones was evaluated against MRC-5 cell lines and was found to be 82% cytotoxic at 1 mg mL(-1)

引用

页码：57 / 62

页数：6

共 16 条

[1]

ABDESSEMED D, 2007, C INT CHIM CIC 1 BAT

[2]

ABDESSEMED D, 2007, ACTA BIOCHIM POL, V54, P47

[3] ANTHRAQUINONE DERIVATIVES FROM GLADIOLUS-SEGETUM [J].

ALI, AA ;

ABDALLAH, OM ;

STEGLICH, W .

PHYTOCHEMISTRY, 1989, 28 (01) :281-282

[4]

Beniston N. T., 1984, FLEURS ALGERIE

[5]

BONNIER G, 1911, TOME ONZIEME

[6] Anthraquinones from Gladiolus gandavensis [J].

Chen, B ;

Wang, DY ;

Ye, Q ;

Li, BG ;

Zhang, GL .

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2005, 7 (03) :197-204

[7]

Chi-Huang T., 2005, BIOORGAN MED CHEM, V13, P3439

[8] A new oleanene triterpene from Gladiolus segetum Ker-Gawl [J].

El-Shanawany, M. A. ;

Hassanean, H. A. ;

Mohamed, M. H. ;

Nafady, A. M. .

NATURAL PRODUCT RESEARCH, 2009, 23 (07) :613-616

[9]

Hong X.C., 2008, WORLD J MICROB BIOT, V24, P419

[10] Highly substituted anthraquinones by anionic cyclization reactions [J].

Krohn, K ;

Boker, N ;

Gauhier, A ;

Schafer, G ;

Werner, F .

JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG, 1996, 338 (04) :349-354

← 1 2 →