SATrans: New Free Available Software for Annotation of Transcriptome and Functional Analysis of Differentially Expressed Genes

被引：0

作者：

Kokas, Filip Zavadil ^{[1
]}

Bergougnoux, Veronique ^{[1
]}

Cudejkova, Maria Majeska ^{[1
]}

机构：

[1] Palacky Univ Olomouc, Ctr Reg Hana Biotechnol & Agr Res, Dept Mol Biol, Slechtitelu 27, Olomouc 78371, Czech Republic

来源：

JOURNAL OF COMPUTATIONAL BIOLOGY | 2019年 / 26卷 / 02期

关键词：

differentially expressed genes; functional annotation; transcriptome; PROTEIN FAMILIES; TOOL; DATABASE;

D O I：

10.1089/cmb.2018.0149

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent technological advances have made next-generation sequencing (NGS) a popular and financially accessible technique allowing a broad range of analyses to be done simultaneously. A huge amount of newly generated NGS data, however, require advanced software support to help both in analyzing the data and biologically interpreting the results. In this article, we describe SATrans (Software for Annotation of Transcriptome), a software package providing fast and robust functional annotation of novel sequences obtained from transcriptome sequencing. Moreover, it performs advanced gene ontology analysis of differentially expressed genes, thereby helping to interpret biologicallyand in a user-friendly formthe quantitative changes in gene expression. The software is freely available and provides the possibility to work with thousands of sequences using a standard personal computer or notebook running on the Linux operating system.

引用

页码：117 / 123

页数：7

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