A lipid transfer protein that transfers lipid

被引：12
|
作者：
Levine, Tim P. [1 ]
机构：
[1] UCL, Inst Ophthalmol, London EC1V 9EL, England
来源：
JOURNAL OF CELL BIOLOGY | 2007年 / 179卷 / 01期
关键词：
D O I：
10.1083/jcb.200709055
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Very few lipid transfer proteins (LTPs) have been caught in the act of transferring lipids in vivo from a donor membrane to an acceptor membrane. Now, two studies (Halter, D., S. Neumann, S. M. van Dijk, J. Wolthoorn, A. M. de Maziere, O.V. Vieira, P. Mattjus, J. Klumperman, G. van Meer, and H. Sprong. 2007. J. Cell Biol. 179: 101 115; D'Angelo, G., E. Polishchuk, G. D. Tullio, M. Santoro, A. D. Campli, A. Godi, G. West, J. Bielawski, C.C. Chuang, A. C. van der Spoel, et al. 2007. Nature. 449: 62 - 67) agree that four-phosphate adaptor protein 2 (FAPP2) transfers glucosylceramide (GlcCer), a lipid that takes an unexpectedly circuitous route.
引用
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页码：11 / 13
页数：3
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