Nickel-catalyzed borylation of arenes and indoles via C-H bond cleavage

被引：136

作者：

Furukawa, Takayuki ^{[1
]}

Tobisu, Mamoru ^{[1
,2
,3
]}

Chatani, Naoto ^{[1
]}

机构：

[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Grad Sch Engn, Ctr Atom & Mol Technol, Suita, Osaka 5650871, Japan

[3] Kyoto Univ, ESICB, Kyoto 6158510, Japan

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 30期

关键词：

SN BONDS; ACTIVATION; FUNCTIONALIZATION; CONSTRUCTION; STANNYLATION; ALKYLATION; ETHERS;

D O I：

10.1039/c5cc01378j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first nickel-catalyzed method for the borylation of carbon-hydrogen bonds in arenes and indoles is described. The use of an N-heterocyclic carbene ligand is essential for an efficient reaction, with an N-cyclohexyl-substituted derivative being optimal. This method is readily applied to the gram scale synthesis of 2-borylindole.

引用

页码：6508 / 6511

页数：4

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