Micropatterning of Electrospun Polyurethane Fibers Through Control of Surface Topography

被引:20
作者
Dempsey, David K. [1 ]
Schwartz, Christian J. [2 ]
Ward, Robert S. [3 ]
Iyer, Ananth V. [3 ]
Parakka, James P. [3 ]
Cosgriff-Hernandez, Elizabeth M. [1 ]
机构
[1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA
[2] Texas A&M Univ, Dept Mech Engn, College Stn, TX 77843 USA
[3] DSM Polymer Technol Grp, Berkeley, CA 94710 USA
关键词
electrospinning; patterning; polyurethanes; soft lithography; tissue engineering; VASCULAR GRAFTS; FABRICATION; DIAMETER; NANOFIBERS; DEPOSITION; SCAFFOLDS;
D O I
10.1002/mame.201000152
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A novel technique was developed to control the deposition of electrospun polyurethane fibers using a silicone collector substrate patterned with soft lithography. This method can be used to control selective fiber deposition with broad pattern dimensions (50-500 mu m) over a large area. The combination of ease of use, low cost, tunability, and generation of relatively large fiber mats available with this technique is expected to advance our ability to mimic the orientation and anisotropic properties of native tissues to generate improved tissue engineering scaffolds.
引用
收藏
页码:990 / 994
页数:5
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