Cell adhesion molecules in cord blood hematopoietic progenitors

We investigated the expression of different cell adhesion molecules on cord blood (CB) and bone marrow (BM) CD34(+)/CD38(+) and CD34(+)/CD38(-) cells. CD11a and CD62L mere more expressed in CB than in BM CD34(+)/CD38(-) subset, suggesting a possible advantage in homing and engraftment, A short exposure to various cytokines increased CD62L expression only in the more differentiated CB and BM CD34(+)/CD38(+) cells.