VIM-12, a novel plasmid-mediated metallo-β-lactamase from Klebsiella pneumoniae that resembles a VIM-1/VIM-2 hybrid

被引:38
作者
Pournaras, S
Ikonomidis, A
Tzouvelekis, LS
Tokatlidou, D
Spanakis, N
Maniatis, AN
Legakis, NJ
Tsakris, A
机构
[1] Univ Thessaloniki, Sch Med, Dept Microbiol, Larisa, Greece
[2] Univ Athens, Sch Med, Dept Microbiol, GR-10679 Athens, Greece
[3] Hippokrateion Hosp, Dept Microbiol, Thessaloniki, Greece
关键词
D O I
10.1128/AAC.49.12.5153-5156.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A transferable plasmid from Klebsiella pneumoniae carried a class 1 integron containing bla(VIM-12), a novel bla(VIM)-type gene, flanked by two copies of aacA7. bla(VIM-12) was clustered between bla(VIM-1) and bLa(VIM-2) and differed from bla(VIM-1) by 18 nucleotides that were all located at the 3' end and matched the corresponding nucleotides in bla(VIM-2). The bla(VIM-12)-associated 59-base element was identical to that described in bla(VIM-2) alleles.
引用
收藏
页码:5153 / 5156
页数:4
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