Palladium-Catalyzed Aerobic Dehydrogenative Cross-Coupling of Polyfluoroarenes with Thiophenes: Facile Access to Polyfluoroarene-Thiophene Structure

被引：84

作者：

He, Chun-Yang ^{[2
]}

Min, Qiao-Qiao ^{[1
]}

Zhang, Xingang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

[2] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China

来源：

ORGANOMETALLICS | 2012年 / 31卷 / 04期

关键词：

ELECTRON-DEFICIENT POLYFLUOROARENES; PROTON-ABSTRACTION MECHANISM; C-H FUNCTIONALIZATION; ARYL BOND FORMATION; DIRECT ARYLATION; DIRECT ALKENYLATION; CRYSTAL-STRUCTURE; SIMPLE ARENES; (HETERO)ARENES; CHEMISTRY;

D O I：

10.1021/om200873j

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We report a Pd-catalyzed aerobic dehydrogenative cross-coupling of polyfluoroarenes with thiophenes via 2-fold C-H functionalization. The advantages of this reaction are its high reaction efficiency, excellent functional group compatibility, and use of molecular O-2 as terminal oxidant. This reaction provides a useful and facile protocol for the preparation of polyfluoroarene thiophene structure of interest in functional materials. Mechanistic studies revealed that the reaction is initiated by the C-H bond cleavage of polyfluoroarenes.

引用

页码：1335 / 1340

页数：6

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