Case report: Experience of a rare case of rebound of the Kasabach-Merritt phenomenon during sirolimus treatment in kaposiform hemangioendothelioma

被引：1

作者：

Wang, Liang ^{[1
]}

Li, Jing ^{[1
]}

Wu, Changhua ^{[1
]}

Song, Dan ^{[1
]}

Liu, Zhuang ^{[1
]}

Niu, Yanli ^{[1
]}

Zhou, Jie ^{[1
]}

Guo, Lei ^{[1
,2
,3
]}

机构：

[1] Shandong Univ, Childrens Hosp, Dept Vasc Anomalies & Intervent Radiol, Jinan, Peoples R China

[2] Jinan Childrens Hosp, Dept Vasc Anomalies & Intervent Radiol, Jinan, Peoples R China

[3] Shandong Prov Clin Res Ctr Childrens Hlth & Dis, Jinan, Peoples R China

来源：

FRONTIERS IN PEDIATRICS | 2022年 / 10卷

关键词：

kaposiform hemangioendothelioma; Kasabach-Merritt phenomenon; embolization; ablation; vincristine; prognosis;

D O I：

10.3389/fped.2022.949950

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm associated with the Kasabach-Merritt phenomenon (KMP), which is a consumptive coagulopathy with associated potentially life-threatening thrombocytopenia. There are no standardized treatment protocols for the management of KHE with KMP. Moreover, there are limited reports regarding the treatment of cases of rebound. Herein, we describe a rare case of rebound of KHE/KMP, during systemic sirolimus treatment, successfully treated with embolization and vincristine infusion combined with microwave ablation.

引用

页数：5

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