Background: HPV infection is closely associated with Cancer Cervix in females. It's the 4th most common cancer after breast, colorectal, and lung cancers in women worldwide. Wherefore (HPV) vaccinations are recommended for routine vaccination at the age of 11 - 12 years for girls as a preventive measure against cervical cancer. Objective: Our objective was to evaluate parents' knowledge, attitudes, and practices about the HPV vaccine as a preventative measure against cervical cancer in Taif City, Saudi Arabia. We aimed to reduce the prevalence of cervical cancer among Saudi Arabians. Methodology: a Cross-sectional study of convenience sample was done Comprised around 350 parents' male or female participants, from Taif city, Saudi Arabia was conducted between November 2021 and to end of January 2022 by using a web-based questionnaire. It was prepared under the supervision of the supervisor and included the demographic data, awareness of HPV infection and cervical cancer as a risk factor, attitude towards the HPV vaccine against HPV infection and practices the HPV vaccine against HPV infection. Results: Our result displayed that only 33.8% of the participants had heard about HPV infection, 26.5 % had heard about the vaccine, and 85% heard about cancer cervix. Conclusion: There is a low level of knowledge amongst our participants regarding HPV and the vaccine. Therefore, we need to apply awareness programs among the population about the HPV infection and the importance of taking the vaccine to decrease the prevalence of cancer cervix in our community.
