Profound effect of plasma protein binding on the polarized transport of furosemide and verapamil in the Caco-2 model

被引：15
作者：
Chung, SM
Park, EJ
Swanson, SM
Wu, TC
Chiou, WL
机构：
[1] Univ Illinois, Coll Pharm, Dept Pharmaceut & Pharmacodynam, Chicago, IL USA
[2] Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL USA
来源：
PHARMACEUTICAL RESEARCH | 2001年 / 18卷 / 04期
关键词：
protein binding; absorptive clearance; permeability; Caco-2; P-glycoprotein; furosemide; verapamil;
D O I：
10.1023/A:1011022931368
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
[No abstract available]
引用
收藏
页码：544 / 547
页数：4
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