Sex-Biased Gene Expression and Sexual Conflict throughout Development

被引：60

作者：

Ingleby, Fiona C. ^{[1
]}

Flis, Ilona ^{[1
]}

Morrow, Edward H. ^{[1
]}

机构：

[1] Univ Sussex, Sch Life Sci, Evolut Behav & Environm Grp, Brighton BN1 9QG, E Sussex, England

来源：

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2015年 / 7卷 / 01期

基金：

欧洲研究理事会; 瑞典研究理事会;

关键词：

GENOME-WIDE ANALYSIS; MALE-LIMITED EVOLUTION; X-LINKED GENES; DROSOPHILA-MELANOGASTER; ANOPHELES-GAMBIAE; TRANSCRIPTIONAL VARIATION; CAENORHABDITIS-ELEGANS; SCHISTOSOMA-MANSONI; MULTIPLE TISSUES; SIZE DIMORPHISM;

D O I：

10.1101/cshperspect.a017632

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Sex-biased gene expression is likely to account for most sexually dimorphic traits because males and females share much of their genome. When fitness optima differ between sexes for a shared trait, sexual dimorphism can allow each sex to express their optimum trait phenotype, and in this way, the evolution of sex-biased gene expression is one mechanism that could help to resolve intralocus sexual conflict. Genome-wide patterns of sex-biased gene expression have been identified in a number of studies, which we review here. However, very little is known about how sex-biased gene expression relates to sex-specific fitness and about how sex-biased gene expression and conflict vary throughout development or across different genotypes, populations, and environments. We discuss the importance of these neglected areas of research and use data from a small-scale experiment on sex-specific expression of genes throughout development to highlight potentially interesting avenues for future research.

引用

页数：17

共 99 条

[11] CONTROLLING THE FALSE DISCOVERY RATE - A PRACTICAL AND POWERFUL APPROACH TO MULTIPLE TESTING [J].

BENJAMINI, Y ;

HOCHBERG, Y .

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 1995, 57 (01) :289-300

[12] Sex Specific Gene Regulation and Expression QTLs in Mouse Macrophages from a Strain Intercross [J].

Bhasin, Jeffrey M. ;

Chakrabarti, Enakshi ;

Peng, Dao-Quan ;

Kulkarni, Aneesh ;

Chen, Xi ;

Smith, Jonathan D. .

PLOS ONE, 2008, 3 (01)

[13] Sex-Biased miRNA Expression in Atlantic Halibut (Hippoglossus hippoglossus) Brain and Gonads [J].

Bizuayehu, T. T. ;

Babiak, J. ;

Norberg, B. ;

Fernandes, J. M. O. ;

Johansen, S. D. ;

Babiak, I. .

SEXUAL DEVELOPMENT, 2012, 6 (05) :257-266

[14] Sex-specific and lineage-specific alternative splicing in primates [J].

Blekhman, Ran ;

Marioni, John C. ;

Zumbo, Paul ;

Stephens, Matthew ;

Gilad, Yoav .

GENOME RESEARCH, 2010, 20 (02) :180-189

[15] Intralocus sexual conflict [J].

Bonduriansky, Russell ;

Chenoweth, Stephen F. .

TRENDS IN ECOLOGY & EVOLUTION, 2009, 24 (05) :280-288

[16] Alternative mRNA fates identified in microRNA-associated transcriptome analysis [J].

Carroll, Adam P. ;

Nham Tran ;

Tooney, Paul A. ;

Cairns, Murray J. .

BMC GENOMICS, 2012, 13

[17] Population and sex differences in Drosophila melanogaster brain gene expression [J].

Catalan, Ana ;

Hutter, Stephan ;

Parsch, John .

BMC GENOMICS, 2012, 13 :1-12

[18] Somatic sex-specific transcriptome differences in Drosophila revealed by whole transcriptome sequencing [J].

Chang, Peter L. ;

Dunham, Joseph P. ;

Nuzhdin, Sergey V. ;

Arbeitman, Michelle N. .

BMC GENOMICS, 2011, 12

[19] Using FlyAtlas to identify better Drosophila melanogaster models of human disease [J].

Chintapalli, Venkateswara R. ;

Wang, Jing ;

Dow, Julian A. T. .

NATURE GENETICS, 2007, 39 (06) :715-720

[20] Negative genetic correlation for adult fitness between sexes reveals ontogenetic conflict in Drosophila [J].

Chippindale, AK ;

Gibson, JR ;

Rice, WR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (04) :1671-1675

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