Of mice and men and larvae: Galleria mellonella to model the early host-pathogen interactions after fungal infection

被引:28
作者
Borman, Andrew M. [1 ]
机构
[1] Publ Hlth England South West, UK Natl Mycol Reference Lab MRL, Bristol, Avon, England
关键词
Candida albicans; Galleria mellonella; fungal pathogenesis; host-pathogen interactions; model organism; proteomics; immunity; CANDIDA-ALBICANS; CRYPTOCOCCUS-NEOFORMANS; ANTIMICROBIAL PEPTIDES; INNATE IMMUNITY; INSECT MODEL; IN-VITRO; DROSOPHILA; VIRULENCE; MECHANISMS; SUSCEPTIBILITY;
D O I
10.1080/21505594.2017.1382799
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:9 / 12
页数:4
相关论文
共 48 条
[1]  
Astvad KMT, 2017, ANTIMICROB AGENTS CH, V61, DOI [10.1128/AAC.00895-17, 10.1128/aac.00895-17]
[2]   Superoxide production in Galleria mellonella hemocytes:: Identification of proteins homologous to the NADPH oxidase complex of human neutrophils [J].
Bergin, D ;
Reeves, EP ;
Renwick, J ;
Wientjes, FB ;
Kavanagh, K .
INFECTION AND IMMUNITY, 2005, 73 (07) :4161-4170
[3]   Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella [J].
Bergin, D ;
Brennan, M ;
Kavanagh, K .
MICROBES AND INFECTION, 2003, 5 (15) :1389-1395
[4]   Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides [J].
Bergin, David ;
Murphy, Lisa ;
Keenan, Joanne ;
Clynes, Martin ;
Kavanagh, Kevin .
MICROBES AND INFECTION, 2006, 8 (08) :2105-2112
[5]   Drosophila as a Model for Human Diseases-Focus on Innate Immunity in Barrier Epithelia [J].
Bergman, P. ;
Esfahani, S. Seyedoleslami ;
Engstrom, Y. .
FLY MODELS OF HUMAN DISEASES, 2017, 121 :29-81
[6]   Galleria mellonella: An invertebrate model to study pathogenicity in correctly defined fungal species [J].
Binder, Ulrike ;
Maurer, Elisabeth ;
Lass-Floerl, Cornelia .
FUNGAL BIOLOGY, 2016, 120 (02) :288-295
[7]   Comparative Pathogenicity of United Kingdom Isolates of the Emerging Pathogen Candida auris and Other Key Pathogenic Candida Species [J].
Borman, Andrew M. ;
Szekely, Adrien ;
Johnson, Elizabeth M. .
MSPHERE, 2016, 1 (04)
[8]   Epidemiology, Antifungal Susceptibility, and Pathogenicity of Candida africana Isolates from the United Kingdom [J].
Borman, Andrew M. ;
Szekely, Adrien ;
Linton, Chistopher J. ;
Palmer, Michael D. ;
Brown, Phillipa ;
Johnson, Elizabeth M. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (03) :967-972
[9]  
Brennan M, 2002, FEMS IMMUNOL MED MIC, V34, P153, DOI 10.1111/j.1574-695X.2002.tb00617.x
[10]   An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes [J].
Browne, Niall ;
Heelan, Michelle ;
Kavanagh, Kevin .
VIRULENCE, 2013, 4 (07) :597-603