Ictal 18F-FDG PET/MRI in a Patient With Cortical Heterotopia and Focal Epilepsy

被引：7

作者：

Calabria, Ferdinando F. ^{[1
]}

Cascini, Giuseppe Lucio ^{[2
]}

Gambardella, Antonio ^{[1
,3
]}

Labate, Angelo ^{[1
,3
]}

Cherubini, Andrea ^{[1
]}

Gulla, Domenico ^{[1
]}

Tafuri, Benedetta ^{[1
]}

Sabatini, Umberto ^{[4
]}

Vescio, Virginia ^{[4
]}

Quattrone, Aldo ^{[1
,3
]}

机构：

[1] CNR, Inst Mol Bioimaging & Physiol, Neuroimaging Res Unit, Rome, Italy

[2] Magna Graecia Univ Catanzaro, Nucl Med Unit, Dept Diagnost Imaging, Catanzaro, Italy

[3] Magna Graecia Univ Catanzaro, Inst Neurol, Dept Med & Surg Sci, Catanzaro, Italy

[4] Magna Graecia Univ Catanzaro, Neuroradiol Unit, Catanzaro, Italy

来源：

CLINICAL NUCLEAR MEDICINE | 2017年 / 42卷 / 10期

关键词：

epilepsy; PET/MRI; F-18-FDG; CMRglu; SUVmax; nodular heterotopia; POSITRON-EMISSION-TOMOGRAPHY; CEREBRAL METABOLIC-RATE; PET;

D O I：

10.1097/RLU.0000000000001797

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 19-year-old man with epilepsy underwent ictal 18F-FDG PET/ MRI, showing a 5 mm heterotopic nodule in the periventricular white matter, adjacent to the frontal horn of the left lateral ventricle (SUVmax, 5.5; glucidic cerebral metabolic rate, 0.317 μmol/mL). A repeated 18F-FDG PET/MRI, during seizure freedom, showed, at visual analysis, subtle decrease of the nodule metabolism. SUVmax and glucidic cerebral metabolic rate were clearly reduced to 3.7 and 0.226, respectively. Ictal 18F-FDG PET/MRI could be useful in epilepsy because of the added value of SUVmax and cerebral metabolic rate of glucose analysis to understand the relationship between heterotopy and epilepsy. © 2017 Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：768 / 769

页数：2

共 11 条

[1] Clinical value of "ictal" FDG positron emission tomography and the routine use of simultaneous scalp EEG studies in patients with intractable partial epilepsies [J].

Barrington, SF ;

Koutroumanidis, M ;

Agathonikou, A ;

Marsden, PK ;

Binnie, CD ;

Polkey, CE ;

Maisey, MN ;

Panayiotopoulos, CP .

EPILEPSIA, 1998, 39 (07) :753-766

[2] Regional Cerebral Metabolic Rate of Glucose Evaluation and Clinical Assessment in Patients With Idiopathic Normal-Pressure Hydrocephalus Before and After Ventricular Shunt Placement A Prospective Analysis [J].

Calcagni, Maria Lucia ;

Taralli, Silvia ;

Mangiola, Annunziato ;

Indovina, Luca ;

Lavalle, Mariadea ;

De Bonis, Pasquale ;

Anile, Carmelo ;

Giordano, Alessandro .

CLINICAL NUCLEAR MEDICINE, 2013, 38 (06) :426-431

[3] Noninvasive quantification of the cerebral metabolic rate for glucose using positron emission tomography, 18F-fluoro-2-deoxyglucose, the Patlak method, and an image-derived input function [J].

Chen, K ;

Bandy, D ;

Reiman, E ;

Huang, SC ;

Lawson, M ;

Feng, D ;

Yun, LS ;

Palant, A .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (07) :716-723

[4] Phenotypic and imaging features of FLNA-negative patients with bilateral periventricular nodular heterotopia and epilepsy [J].

Fallil, Zianka ;

Pardoe, Heath ;

Bachman, Robert ;

Cunningham, Benjamin ;

Parulkar, Isha ;

Shain, Catherine ;

Poduri, Annapurna ;

Knowlton, Robert ;

Kuzniecky, Ruben .

EPILEPSY & BEHAVIOR, 2015, 51 :321-327

[5] Cerebral metabolism and perfusion in MR-negative individuals with refractory focal epilepsy assessed by simultaneous acquisition of 18F-FDG PET and arterial spin labeling [J].

Galazzo, Ilaria Boscolo ;

Mattoli, Maria Vittoria ;

Pizzini, Francesca Benedetta ;

De Vita, Enrico ;

Barnes, Anna ;

Duncan, John S. ;

Jager, Hans Rolf ;

Golay, Xavier ;

Bomanji, Jamshed B. ;

Koepp, Matthias ;

Groves, Ashley M. ;

Fraioli, Francesco .

NEUROIMAGE-CLINICAL, 2016, 11 :648-657

[6] All-in-one interictal presurgical imaging in patients with epilepsy: single-session EEG/PET/(f)MRI [J].

Grouiller, Frederic ;

Delattre, Benedicte M. A. ;

Pittau, Francesca ;

Heinzer, Susanne ;

Lazeyras, Francois ;

Spinelli, Laurent ;

Iannotti, Giannina R. ;

Seeck, Margitta ;

Ratib, Osman ;

Vargas, Maria I. ;

Garibotto, Valentina ;

Vulliemoz, Serge .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 (07) :1133-1143

[7] Planned ictal FDG PET imaging for localization of extratemporal epileptic foci [J].

Meltzer, CC ;

Adelson, D ;

Brenner, RP ;

Crumrine, PK ;

Van Cott, A ;

Schiff, DP ;

Townsend, DW ;

Scheuer, ML .

EPILEPSIA, 2000, 41 (02) :193-200

[8] Ictal PET in Ohtahara Syndrome With Hemimegalencephaly [J].

Roy, Shambo Guha ;

Tripathi, Madhavi ;

Tripathi, Manjari ;

Ramanujam, Bhargavi ;

Singhal, Abhinav ;

Bal, Chandrasekhar .

CLINICAL NUCLEAR MEDICINE, 2017, 42 (05) :E263-E264

[9] [DEOXYGLUCOSE-C-14 METHOD FOR MEASUREMENT OF LOCAL CEREBRAL GLUCOSE-UTILIZATION - THEORY, PROCEDURE, AND NORMAL VALUES IN CONSCIOUS AND ANESTHETIZED ALBINO-RAT [J].

SOKOLOFF, L ;

REIVICH, M ;

KENNEDY, C ;

DESROSIERS, MH ;

PATLAK, CS ;

PETTIGREW, KD ;

SAKURADA, O ;

SHINOHARA, M .

JOURNAL OF NEUROCHEMISTRY, 1977, 28 (05) :897-916

[10] Subclinical Seizures as a Pitfall in 18F-FDG PET Imaging of Temporal Lobe Epilepsy [J].

Tafti, Bashir Akhavan ;

Mandelkern, Mark ;

Berenji, Gholam Reza .

CLINICAL NUCLEAR MEDICINE, 2014, 39 (09) :819-821

← 1 2 →