Complications of Immunosuppression in Glomerular Disease

被引：43

作者：

Jefferson, J. Ashley ^{[1
]}

机构：

[1] Univ Washington, Dept Med, Div Nephrol, Seattle, WA 98195 USA

来源：

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2018年 / 13卷 / 08期

关键词：

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; ANTIBODY-ASSOCIATED VASCULITIS; PROLIFERATIVE LUPUS NEPHRITIS; LATE-ONSET NEUTROPENIA; PNEUMOCYSTIS-JIROVECII PNEUMONIA; DAILY ORAL CYCLOPHOSPHAMIDE; ANCA-ASSOCIATED VASCULITIS; TERM-FOLLOW-UP; MYCOPHENOLATE-MOFETIL; MEMBRANOUS NEPHROPATHY;

D O I：

10.2215/CJN.01920218

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Most glomerular diseases are immunologically mediated disorders of the kidney and are common causes of ESKD. In addition to supportive therapy, a wide range of immunosuppressive agents are used in the management of patients with these conditions. Immunosuppression requires a careful balance of risk and benefits, and many of these agents have a narrow therapeutic window and require close monitoring. This review describes the side effects of immunosuppressive agents used in recent randomized, controlled trials of glomerular disease, and highlights some of the key adverse events that determine the choice and prescription of these medications.

引用

页码：1264 / 1275

页数：12

共 77 条

[1] Long-term follow-up of patients who received repeat-dose rituximab as maintenance therapy for ANCA-associated vasculitis [J].

Alberici, Federico ;

Smith, Rona M. ;

Jones, Rachel B. ;

Roberts, Darren M. ;

Willcocks, Lisa C. ;

Chaudhry, Afzal ;

Smith, Kenneth G. C. ;

Jayne, David R. W. .

RHEUMATOLOGY, 2015, 54 (07) :1153-1160

[2] Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis [J].

Appel, Gerald B. ;

Contreras, Gabriel ;

Dooley, Mary Anne ;

Ginzler, Ellen M. ;

Isenberg, David ;

Jayne, David ;

Li, Lei-Shi ;

Mysler, Eduardo ;

Sanchez-Guerrero, Jorge ;

Solomons, Neil ;

Wofsy, David .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 20 (05) :1103-1112

[3] Treatment of Lupus Nephritis With Abatacept [J].

Askanase, Anca D. ;

Byron, Margie ;

Keyes-Elstein, Lynette L. ;

Cagnoli, Patricia C. ;

McCune, W. Joseph ;

Chatham, W. Winn ;

Contreras, Gabriel ;

Daikh, David I. ;

Dall'Era, Maria ;

Wofsy, David ;

Davidson, Anne ;

Diamond, Betty ;

Mackay, Meggan ;

Ding, Linna ;

Gao, Wendy ;

Dooley, Mary Anne ;

Fragoso-Loyo, Hilda ;

Sanchez-Guerrero, Jorge ;

Karp, David R. ;

Olsen, Nancy J. ;

Jolly, Meenakshi ;

Kalunian, Kenneth ;

Kamen, Diane ;

Lee, Iris ;

Levesque, Marc C. ;

Lim, S. Sam ;

Ramos-Remus, Cesar ;

Rovin, Brad H. ;

Sayre, Peter H. ;

Smilek, Dawn E. ;

Tosta, Patti ;

Utset, Tammy O. ;

Venuturupalli, Swamy ;

Winchester, Robert .

ARTHRITIS & RHEUMATOLOGY, 2014, 66 (11) :3096-3104

[4] Infections associated with the use of eculizumab: recommendations for prevention and prophylaxis [J].

Benamu, Esther ;

Montoya, Jose G. .

CURRENT OPINION IN INFECTIOUS DISEASES, 2016, 29 (04) :319-329

[5] RISK FOR SUSTAINED AMENORRHEA IN PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS RECEIVING INTERMITTENT PULSE CYCLOPHOSPHAMIDE THERAPY [J].

BOUMPAS, DT ;

AUSTIN, HA ;

VAUGHAN, EM ;

YARBORO, CH ;

KLIPPEL, JH ;

BALOW, JE .

ANNALS OF INTERNAL MEDICINE, 1993, 119 (05) :366-369

[6] 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis [J].

Buckley, Lenore ;

Guyatt, Gordon ;

Fink, Howard A. ;

Cannon, Michael ;

Grossman, Jennifer ;

Hansen, Karen E. ;

Humphrey, Mary Beth ;

Lane, Nancy E. ;

Magrey, Marina ;

Miller, Marc ;

Morrison, Lake ;

Rao, Madhumathi ;

Robinson, Angela Byun ;

Saha, Sumona ;

Wolver, Susan ;

Bannuru, Raveendhara R. ;

Vaysbrot, Elizaveta ;

Osani, Mikala ;

Turgunbaev, Marat ;

Miller, Amy S. ;

McAlindon, Timothy .

ARTHRITIS & RHEUMATOLOGY, 2017, 69 (08) :1521-1537

[7] Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project [J].

Carson, Kenneth R. ;

Evens, Andrew M. ;

Richey, Elizabeth A. ;

Habermann, Thomas M. ;

Focosi, Daniele ;

Seymour, John F. ;

Laubach, Jacob ;

Bawn, Susie D. ;

Gordon, Leo I. ;

Winter, Jane N. ;

Furman, Richard R. ;

Vose, Julie M. ;

Zelenetz, Andrew D. ;

Mamtani, Ronac ;

Raisch, Dennis W. ;

Dorshimer, Gary W. ;

Rosen, Steven T. ;

Muro, Kenji ;

Gottardi-Littell, Numa R. ;

Talley, Robert L. ;

Sartor, Oliver ;

Green, David ;

Major, Eugene O. ;

Bennett, Charles L. .

BLOOD, 2009, 113 (20) :4834-4840

[8] Rituximab for remission induction and maintenance in refractory granulomatosis with polyangiitis (Wegener's) Ten-year experience at a single center [J].

Cartin-Ceba, Rodrigo ;

Golbin, Jason M. ;

Keogh, Karina A. ;

Peikert, Tobias ;

Sanchez-Menendez, Marta ;

Ytterberg, Steven R. ;

Fervenza, Fernando C. ;

Specks, Ulrich .

ARTHRITIS AND RHEUMATISM, 2012, 64 (11) :3770-3778

[9] Rituximab for induction and maintenance treatment of ANCA-associated vasculitides: a multicentre retrospective study on 80 patients [J].

Charles, Pierre ;

Neel, Antoine ;

Tieulie, Nathalie ;

Hot, Arnaud ;

Pugnet, Gregory ;

Decaux, Olivier ;

Marie, Isabelle ;

Khellaf, Mehdi ;

Kahn, Jean-Emmanuel ;

Karras, Alexandre ;

Ziza, Jean-Marc ;

Deligny, Christophe ;

Tcherakian, Colas ;

Guillevin, Loic .

RHEUMATOLOGY, 2014, 53 (03) :532-539

[10] Sequential therapies for proliferative lupus nephritis [J].

Contreras, G ;

Pardo, V ;

Leclercq, B ;

Lenz, O ;

Tozman, E ;

O'Nan, P ;

Roth, D .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (10) :971-980

← 1 2 3 4 5 6 7 8 →