Community Participation in Two Vaccination Trials in Slums of Kolkata, India: A Multi-level Analysis

被引：11

作者：

Ali, Mohammad ^{[1
]}

Sur, Dipika ^{[2
]}

Lopez, Anna Lena ^{[1
]}

Kanungo, Suman ^{[2
]}

Ochiai, R. Leon ^{[1
]}

Manna, Byomkesh ^{[2
]}

Kim, Deok Ryun ^{[1
]}

Deen, Jacqueline ^{[1
]}

Bhattacharya, Sujit K. ^{[3
]}

Clemens, John D. ^{[1
]}

机构：

[1] Int Vaccine Inst, Seoul 151818, South Korea

[2] Natl Inst Cholera & Enter Dis, Kolkata 700010, India

[3] Indian Council Med Res, New Delhi 110029, India

来源：

JOURNAL OF HEALTH POPULATION AND NUTRITION | 2010年 / 28卷 / 05期

基金：

比尔及梅琳达.盖茨基金会;

关键词：

Cholera; Cholera vaccines; Typhoid fever; Typhoid-paratyphoid vaccines; Vaccination; India; VI CAPSULAR POLYSACCHARIDE; DEVELOPING-COUNTRIES; SALMONELLA-TYPHI; FEVER; EFFICACY; VACCINES; HIV;

D O I：

10.3329/jhpn.v28i5.6153

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

This study aims at understanding the individual and community-level characteristics that influenced participation in two consecutive vaccine trials (typhoid and cholera) in urban slums of Kolkata, India. The study area was divided into 80 geographic clusters (communities), with 59,533 subjects aged >= 2 years for analysis. A multi-level model was employed in which the individuals were seen nested within the cluster. Rates of participation in both the trials were nearly the same; those who participated in the initial trial were likely to participate in the subsequent cholera vaccine trial. Communities with predominantly Hindu population, lower percentage of households with an educated household head, or lower percentage of households owning a motorbike had higher participation than their counterparts. At individual scale, higher participation was observed among younger subjects, females, and individuals from households with a household head who had no or minimal education. Geographic patterns were also observed m participation in the trials. The results illustrated that participation in the trial was mostly influenced by various individual and community-level factors, which need to be addressed for a successful vaccination campaign.

引用

页码：450 / 457

页数：8

共 21 条

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