An approach to the synthesis of 4-aryl and 5-aryl substituted thiazole-2(3H)-thiones employing flow processing

被引：3

作者：

Balti, Monaem ^{[1
]}

Miller, Shelli A. ^{[2
]}

Efrit, Mohamed Lotfi ^{[1
]}

Leadbeater, Nicholas E. ^{[2
]}

机构：

[1] Univ Tunis El Manar, Lab Organ Synth & Heterocycl Chem, Fac Sci Tunis, Dept Chem, Tunis 1060, Tunisia

[2] Univ Connecticut, Dept Chem, 55 North Eagleville Rd, Storrs, CT 06269 USA

来源：

RSC ADVANCES | 2016年 / 6卷 / 76期

关键词：

INDOLEAMINE 2,3-DIOXYGENASE; CRYSTAL-STRUCTURES; BENZO-1,3-THIAZOLINE-2-THIONE; TAUTOMERISM; DERIVATIVES; COMPLEXES; FLUORINE; HEALTH; SALTS;

D O I：

10.1039/c6ra15488c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the preparation of 4-aryl and 5-aryl substituted thiazole-2(3H)-thiones is described. Flow processing is employed as a tool, and supported acids and bases used to facilitate both the synthetic strategy and product isolation. The methodology is applicable to a range of substrates.

引用

页码：72165 / 72169

页数：5

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