An approach to the synthesis of 4-aryl and 5-aryl substituted thiazole-2(3H)-thiones employing flow processing

被引：3
|
作者：
Balti, Monaem [1 ]
Miller, Shelli A. [2 ]
Efrit, Mohamed Lotfi [1 ]
Leadbeater, Nicholas E. [2 ]
机构：
[1] Univ Tunis El Manar, Lab Organ Synth & Heterocycl Chem, Fac Sci Tunis, Dept Chem, Tunis 1060, Tunisia
[2] Univ Connecticut, Dept Chem, 55 North Eagleville Rd, Storrs, CT 06269 USA
来源：
RSC ADVANCES | 2016年 / 6卷 / 76期
关键词：
INDOLEAMINE 2,3-DIOXYGENASE; CRYSTAL-STRUCTURES; BENZO-1,3-THIAZOLINE-2-THIONE; TAUTOMERISM; DERIVATIVES; COMPLEXES; FLUORINE; HEALTH; SALTS;
D O I：
10.1039/c6ra15488c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for the preparation of 4-aryl and 5-aryl substituted thiazole-2(3H)-thiones is described. Flow processing is employed as a tool, and supported acids and bases used to facilitate both the synthetic strategy and product isolation. The methodology is applicable to a range of substrates.
引用
收藏
页码：72165 / 72169
页数：5
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