Imaging evaluation of lung cancer treated with PD-1/PD-L1 inhibitors

被引：4

作者：

Mohammed, Nader ^{[1
]}

Zhou, Rong Rong ^{[2
]}

Xiong, Zeng ^{[1
]}

机构：

[1] Cent South Univ, Xiangya Hosp, Dept Radiol, Changsha, Peoples R China

[2] Cent South Univ, Xiangya Hosp, Dept Oncol, Changsha, Peoples R China

来源：

BRITISH JOURNAL OF RADIOLOGY | 2021年 / 94卷 / 1127期

关键词：

IMMUNE-RELATED RESPONSE; ADVERSE EVENTS; CHECKPOINT INHIBITORS; TUMOR RESPONSE; HYPERPROGRESSIVE DISEASE; EVALUATION CRITERIA; ADVANCED MELANOMA; IMMUNOTHERAPY; PNEUMONITIS; NIVOLUMAB;

D O I：

10.1259/bjr.20210228

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Immunotherapy (PD-1/PD- L1 inhibitors) has attracted attention for lung cancer treatment and recasted the administration of immunotherapeutics to patients who have advanced/metastatic diseases. Whether in combination or as monotherapy, these medications have become common therapies for certain patients with lung cancer. Moreover, their usage is expected to expand widely in the future. This review aims to discuss the imaging evaluation of lung cancer response to PD-1/PD- L1 therapy with focus on new radiological criteria for immunotherapy response. Abnormal radiological responses (pseudoprogression, dissociative responses, and hyperprogression) and immune-related adverse events are also described.

引用

页数：9

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