The development of InAsSb detectors based on the nBn design for the mid-wave infrared (MWIR) spectral region is discussed. Comparisons of optical and electrical properties of InAsSb photodetectors with two different barrier material, namely, AlAs0.15Sb0.75 (structure A) and AlAs0.10Sb0.9 (structure B) are reported. The dark current density in the AlAs0.15Sb0.85 is lower possibly due to the larger valence band offset. Clear room temperature spectral responses is observed and a specific detectivity (D*) of 1.4x10(12) and 1.01x10(12) cmHz(1/2)/W at 0.2 V, and a responsivity of 0.87 and 1.66 A/W under 0.2 V biasing at 77 K and 3.5 mu m, assuming unity gain, was obtained for structures A and B, respectively.