Developmental decisions in Dictyostelium discoideum

被引：53
作者：
Strmecki, L [1 ]
Greene, DM [1 ]
Pears, CJ [1 ]
机构：
[1] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England
来源：
DEVELOPMENTAL BIOLOGY | 2005年 / 284卷 / 01期
基金：
英国惠康基金;
关键词：
Dictyostelium; differentiation; prestalk; prespore; Gsk-3; STAT; cAMP; DIF; cell cycle;
D O I：
10.1016/j.ydbio.2005.05.011
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Dictyostelium discoideum is an excellent system in which to study developmental decisions. Synchronous development is triggered by starvation and rapidly generates a limited number of cell types. Genetic and image analyses have revealed the elegant intricacies associated with this simple development system. Key signaling pathways identified as regulating cell fate decisions are likely to be conserved with metazoa and are providing insight into differentiation decisions under circumstances where considerable cell movement takes place during development. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码：25 / 36
页数：12
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