Ingestion of a Moderately High Caffeine Dose Before Exercise Increases Postexercise Energy Expenditure

Caffeine is an ergogenic aid widely used before and during prolonged exercise. Due to its prolonged biological half-life caffeine effects could remain after exercise. We aimed to investigate the metabolic, respiratory, and cardiovascular postexercise responses to preexercise graded caffeine ingestion. Twelve aerobically trained subjects (mean VO2max = 54 7 ml . min(-1) . kg(-1)) cycled for 60-min at 75% VO2max after ingesting placebo (0 mg of caffeine per kg of body weight) or 0.5, 1.5, 3.0 and 4.5 mg . kg(-1) on five occasions. During the 3 hr postexercise, heart rate, blood pressure, glucose, lactate, and fatty acids were analyzed. None of these variables were statistically affected by preexercise caffeine ingestion between 0.5 and 4.5 mg . kg(-1). However, ingestion of 4.5 mg . kg(-1) of caffeine raised postexercise energy expenditure 15% above placebo (233 +/- 58 vs. 202 +/- 49 kcal/3 hr; p < .05). Ventilation and tidal volume were elevated after the 4.5 mg.kg(-1) caffeine dose above placebo (9.2 +/- 2.5 L . min(-1) and 0.67 +/- 0.29 L . breath(-1) vs. 7.8 +/- 1.5 L . min(-1) and 0.56 +/- 0.20 L . breath(-1), respectively; p < .05). Ventilation correlated with tidal volume (r = .45; p < .05) and energy expenditure (r = .72; p < .05). In summary, preexercise ingestion of ergogenic caffeine doses do not alter postexercise cardiovascular responses. However, ingestion of 4.5 mg . kg(-1) of caffeine raises 3-hr postexercise energy expenditure (i.e., 31 kcal) likely through increased energy cost of ventilation.