A critical overview of recent investigations into the genetics of schizophrenia

被引：11
作者：
DeLisi, LE [1 ]
机构：
[1] SUNY Stony Brook, Hlth Sci Ctr, Dept Psychiat, Stony Brook, NY 11794 USA
来源：
CURRENT OPINION IN PSYCHIATRY | 1999年 / 12卷 / 01期
关键词：
D O I：
10.1097/00001504-199901000-00014
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
It has long been known that a genetic predisposition exists for schizophrenia, but the mechanism for inheritance and what is inherited remains elusive. Several advances have been made recently in the fields of molecular genetics and psychiatric genetics, as well as politically, which lends optimism to the hope that one or more responsible genes may soon be identified. These will hopefully revolutionize the treatment of this debilitating disorder and lead to preventive measures for those genetically at risk. Curr Opin Psychiatry 12:29-39. (C) 1999 Lippincott Williams & Wilkins.
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收藏
页码：29 / 39
页数：11
相关论文
共 117 条
  • [81] Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysis
    Schwab, SG
    Eckstein, GN
    Hallmayer, J
    Lerer, B
    Albus, M
    Borrmann, M
    Lichtermann, D
    Ertl, MA
    Maier, W
    Wildenauer, DB
    [J]. MOLECULAR PSYCHIATRY, 1997, 2 (02) : 156 - 160
  • [82] Schwab SG, 1998, AM J MED GENET, V81, P302, DOI 10.1002/(SICI)1096-8628(19980710)81:4<302::AID-AJMG5>3.0.CO
  • [83] 2-V
  • [84] SCHWARTZ CE, 1993, AM J HUM GENET, V52, P1025
  • [85] Seidman LJ, 1997, AM J MED GENET, V74, P507, DOI 10.1002/(SICI)1096-8628(19970919)74:5<507::AID-AJMG11>3.0.CO
  • [86] 2-G
  • [87] Schizophrenia in Surinamese and Dutch Antillean immigrants to the Netherlands: Evidence of an increased incidence
    Selten, JP
    Slaets, JPJ
    Kahn, RS
    [J]. PSYCHOLOGICAL MEDICINE, 1997, 27 (04) : 807 - 811
  • [88] SHAW SH, 1998, IN PRESS AM J MED GE
  • [89] LOCALIZATION OF A SUSCEPTIBILITY LOCUS FOR SCHIZOPHRENIA ON CHROMOSOME-5
    SHERRINGTON, R
    BRYNJOLFSSON, J
    PETURSSON, H
    POTTER, M
    DUDLESTON, K
    BARRACLOUGH, B
    WASMUTH, J
    DOBBS, M
    GURLING, H
    [J]. NATURE, 1988, 336 (6195) : 164 - 167
  • [90] Lateral ventricular enlargement in schizophrenic probands and their siblings with schizophrenia-related disorders
    Silverman, JM
    Smith, CJ
    Guo, SL
    Mohs, RC
    Siever, LJ
    Davis, KL
    [J]. BIOLOGICAL PSYCHIATRY, 1998, 43 (02) : 97 - 106
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