The Possible Risk of Cancer in Claudicants

被引：11

作者：

Taute, Bettina-Maria ^{[1
]}

Thommes, Stephan ^{[1
]}

Taute, Ralf ^{[1
]}

Podhaisky, Hubert ^{[1
]}

机构：

[1] Univ Halle Wittenberg, Univ Clin, Dept Internal Med Angiol 3, D-06120 Halle, Saale, Germany

来源：

ANGIOLOGY | 2011年 / 62卷 / 07期

关键词：

peripheral arterial disease; intermittent claudication; secondary prevention; cancer death; vascular death; PERIPHERAL ARTERIAL-DISEASE; INTERMITTENT CLAUDICATION; OCCLUSIVE DISEASE; LUNG-CANCER; MORTALITY; PROGNOSIS; ATHEROSCLEROSIS; ASSOCIATION; MANAGEMENT; SMOKING;

D O I：

10.1177/0003319711400308

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The aim of this study was to select a group of patients who had mild intermittent claudication and were undergoing secondary prevention measures, and record all vascular and non-vascular events over a 10-year follow-up. A total of 534 events were recorded in 109 claudicants. 25.7% of the claudicants died, 39% of them due to vascular events, 36% from cancer and 25% from other causes. 17 of the 20 cancer cases could be classified as related to smoking. Cancer occurred relatively early in the study, within the first five years, while severe vascular events occurred mainly during later periods. A clear transformation occurred in the outcome of the claudicants. Mortality was equally attributable to vascular and cancer-related comorbidities. In conclusion, the improvement of vascular outcomes due to secondary prevention measures and technological advances in the management of acute vascular events may result in a relative increase in cancer incidence and deaths.

引用

页码：579 / 584

页数：6

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