Solubilities of adefovir dipivoxil in different binary solvents at 298.15 K

被引：14

作者：

Hou, Guangyang ^{[1
]}

Yin, Qiuxiang ^{[1
]}

Yang, Yu ^{[1
]}

Hu, Yang ^{[1
]}

Zhang, Meijing ^{[1
]}

Wang, Jingkang ^{[1
]}

机构：

[1] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2008年 / 53卷 / 04期

关键词：

D O I：

10.1021/je700664g

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubility data of adefovir dipivoxil in five different binary mixed solvents formed by isopropyl ether with ethanol, 2-propanol, dichloromethane, ethyl acetate, and acetone at 298.15 K were measured with the mole fraction of isopropyl ether ranging from 0.000 to 1.000. A laser monitoring observation technique was used to determine the dissolution of the solid phase in a solid + liquid mixture. The solubility data were correlated with a function of the binary solvent mole fractions by the combined nearly ideal binary solvent (NIBS)/Redlich-Kister equation.

引用

页码：1021 / 1023

页数：3

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