The validity of the DSM-IV diagnostic classification system of non-affective psychoses

被引:25
作者
Korver-Nieberg, Nikie [1 ]
Quee, Piotr J. [2 ]
Boos, Heleen B. [3 ]
Simons, Claudia J. [4 ]
Kahn, Rene S. [3 ]
Cahn, Wiepke [3 ]
Linszen, Don H. [1 ]
de Haan, Lieuwe [1 ]
van Os, Jim [4 ]
Krabbendam, Lydia [4 ]
Myin-Germeys, Inez [4 ]
Wiersma, Durk [2 ]
Bruggemen, Richard [2 ]
van den Berg, S. E. [1 ]
Schroeder, C. L. A. [1 ]
van der Valk, R. [1 ]
Dekker, N. [1 ]
Meijer, C. J. [1 ]
Korver, N. [1 ]
Boyette, L. N. [1 ]
Meijer, J. [1 ]
van Dam, D. [1 ]
de Rijke, I. [1 ]
Huinink, S. [1 ]
de Vries, I. [1 ]
Jansen, M. [1 ]
Bos, D. [1 ]
Hoen, W. P. [1 ]
te West, E. M. [1 ]
Groeneveld, S. H. J. [1 ]
Vergunst, E. M. [1 ]
Swets, M. [1 ]
Vothknecht, S. [1 ]
Poleacov, I. [1 ]
van Dijk, D. [1 ]
de Metz, S. [1 ]
Hasty, M. T. [1 ]
Geertsa, G. [1 ]
de Baaij, P. M. [1 ]
Metzger, A. [1 ]
van Beveren, N. J. M. [1 ]
Baldini, M. [1 ]
Grimbergen, F. D. [1 ]
Boerma, M. A. M. [1 ]
Agsteribbe, C. [1 ]
Wisman, H. P. [1 ]
Monden, M. A. H. [1 ]
Bosman, M. M. [1 ]
van Dijk, M. [1 ]
Klaassen, R. [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Psychiat, Meibergdreef 5, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, NL-9700 AB Groningen, Netherlands
[3] Univ Med Ctr Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, Utrecht, Netherlands
[4] Maastricht Univ, Med Ctr, S Limburg Mental Hlth Res & Teaching Network, EURON, Maastricht, Netherlands
关键词
categorization; DSM-V; schizophrenia; subtypes; validity; NEGATIVE-SYNDROME-SCALE; SCHIZOAFFECTIVE DISORDER; PREMORBID ADJUSTMENT; BIPOLAR DISORDER; 5-FACTOR MODEL; SCHIZOPHRENIA; RELIABILITY;
D O I
10.3109/00048674.2011.620562
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: The schizophrenia and other non-affective disorders categories listed in the DSM-IV, are currently under revision for the development of the fifth edition. The aim of the present study is to demonstrate the validity of these categories by investigating possible differences between diagnostic patient subgroups on various measures. Methods: 1064 patients with a diagnosis of non-affective psychosis (schizophrenia N = 731 (paranoid type 82%), schizoaffective N = 63, schizophreniform N = 120, psychosis not otherwise specified/brief psychotic disorder N = 150) participated in this study. Dependent variables were demographic and clinical characteristics, severity of psychopathology, premorbid and current functioning, and indicators of quality of life. Results: Within the diagnostic group of schizophrenia, no significant differences were observed between paranoid schizophrenia, disorganized, and undifferentiated schizophrenia. Patients with schizophrenia experienced more severe psychopathology and had poorer levels of current functioning compared to patients with psychosis not otherwise specified or brief psychotic disorder. Differences between schizophrenia and schizoaffective disorder were less clear. Conclusion: Our results do not support the validity of schizophrenia subtypes. Schizophrenia can be distinguished from brief psychotic disorder and psychotic disorder not otherwise specified. These findings may fuel the actual DSM-V discussion.
引用
收藏
页码:1061 / 1068
页数:8
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