Targeting for drug delivery and imaging: an overview of the state of the art in cancer

被引：4

作者：

Dubernet, Catherine ^{[1
]}

机构：

[1] Univ Paris Sud, CNRS, UMR 8612, F-92296 Chatenay Malabry, France

来源：

BULLETIN DU CANCER | 2011年 / 98卷 / 11期

关键词：

targeting; cancer; nanotechnology; diagnostics; stealth; DOXORUBICIN-LOADED NANOPARTICLES; CELLS IN-VITRO; MULTIFUNCTIONAL NANOCARRIERS; THERAPY; NANOMEDICINE; DIAGNOSIS; TUMORS; THERAPEUTICS; PACLITAXEL; RESISTANCE;

D O I：

10.1684/bdc.2011.1468

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The concept of drug targeting has resulted in a considerable variety of tools within nanotechnology, whose potentials in the special field of cancer are very interesting. There is a strong link between the structure and the surface of the vector on the one hand, and the biological target thus accessible on the other hand, as illustrated a number of typical examples. Parallel developments were made in the fields of therapy and diagnosis, stage by stage. The challenges now live in the combination of approaches widely reported under the terminology of "theranostics". triangle

引用

页码：1363 / 1371

页数：9

共 43 条

[1] PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect [J].

Acharya, Sarbari ;

Sahoo, Sanjeeb K. .

ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (03) :170-183

[2] Increase of doxorubicin sensitivity by doxorubicin-loading into nanoparticles for hepatocellular carcinoma cells in vitro and in vivo [J].

Barraud, L ;

Merle, P ;

Soma, E ;

Lefrançois, L ;

Guerret, S ;

Chevallier, M ;

Dubernet, C ;

Couvreur, P ;

Trépo, C ;

Vitvitski, L .

JOURNAL OF HEPATOLOGY, 2005, 42 (05) :736-743

[3] Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging [J].

Bhaskar, Sonu ;

Tian, Furong ;

Stoeger, Tobias ;

Kreyling, Wolfgang ;

de la Fuente, Jesus M. ;

Grazu, Valeria ;

Borm, Paul ;

Estrada, Giovani ;

Ntziachristos, Vasilis ;

Razansky, Daniel .

PARTICLE AND FIBRE TOXICOLOGY, 2010, 7

[4] Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: An original drug delivery pathway [J].

Bildstein, L. ;

Dubernet, C. ;

Marsaud, V. ;

Chacun, H. ;

Nicolas, V. ;

Gueutin, C. ;

Sarasin, A. ;

Benech, H. ;

Lepetre-Mouelhi, S. ;

Desmaele, D. ;

Couvreur, P. .

JOURNAL OF CONTROLLED RELEASE, 2010, 147 (02) :163-170

[5] Polymers and nanoparticles: Intelligent tools for intracellular targeting? [J].

Breunig, M. ;

Bauer, S. ;

Goefferich, A. .

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2008, 68 (01) :112-128

[6] Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting [J].

Brigger, I ;

Morizet, J ;

Aubert, G ;

Chacun, H ;

Terrier-Lacombe, MJ ;

Couvreur, P ;

Vassal, G .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 303 (03) :928-936

[7] Nanoparticles in cancer therapy and diagnosis [J].

Brigger, I ;

Dubernet, C ;

Couvreur, P .

ADVANCED DRUG DELIVERY REVIEWS, 2002, 54 (05) :631-651

[8] HEPATIC TISSUE DISTRIBUTION OF DOXORUBICIN-LOADED NANOPARTICLES AFTER IV ADMINISTRATION IN RETICULOSARCOMA M-5076 METASTASIS-BEARING MICE [J].

CHIANNILKULACHAI, N ;

AMMOURY, N ;

CAILLOU, B ;

DEVISSAGUET, JP ;

COUVREUR, P .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1990, 26 (02) :122-126

[9] Recent advances in iron oxide nanocrystal technology for medical imaging [J].

Corot, Claire ;

Robert, Philippe ;

Idee, Jean-Marc ;

Port, Marc .

ADVANCED DRUG DELIVERY REVIEWS, 2006, 58 (14) :1471-1504

[10] Discovery of new hexagonal supramolecular nanostructures formed by squalenoylation of an anticancer nucleoside analogue [J].

Couvreur, Patrick ;

Reddy, L. Harivardhan ;

Mangenot, Sephanie ;

Poupaert, Jacques H. ;

Desmaele, Didier ;

Lepetre-Mouelhi, Sinda ;

Pili, Barbara ;

Bourgaux, Claudie ;

Amenitsch, H. ;

Ollivon, Michel .

SMALL, 2008, 4 (02) :247-253

← 1 2 3 4 5 →