SYNTHESIS AND SCREENING OF ANTIMICROBIAL ACTIVITY OF NOVEL PYRROLYL-PYRAZOLE DERIVATIVES

被引：0

作者：

Hallikeri, C. S. ^{[1
,2
]}

Joshi, Shrinivas D. ^{[2
]}

Kumar, Devendra ^{[2
]}

Kulkarni, V. H. ^{[2
]}

Selvam, Theivendren Paneer ^{[3
]}

机构：

[1] Prist Univ, Ctr Res & Dev, Thanjavur 613403, Tamil Nadu, India

[2] SETs Coll Pharm, Dept Pharmaceut Chem, Novel Drug Design & Discovery Lab, Dharwad 580002, Karnataka, India

[3] PESs Rajaram & Tarabai Bandekar Coll Pharm, Ponda, Goa, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 24卷 / 03期

关键词：

ACID HYDRAZIDE ANALOGS; ANTITUBERCULAR AGENTS; POTENTIAL ANTIBACTERIAL; RING-SYSTEMS; TUBERCULOSIS; OXADIAZOLE; TRIAZOLE;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel pyrrolyl-pyrazole derivatives (5a-k) were synthesized by reacting substituted chalcones (3a-k) and 4-pyrrol-1-yl benzoic acid hydrazide (4) in ethanol. Purity of newly synthesized compounds were confirmed by TLC and melting point. The structures of all newly synthesized compounds were confirmed by spectral study such as IR, H-1 NMR and Mass spectroscopy. The title compounds were screened for their antibacterial and antitubercular activities.

引用

页码：261 / 264

页数：4

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