Zooming in on dendritic cells for CD40 agonists

被引：3
|
作者：
Hubner, Julian [1 ]
Nimmerjahn, Falk [1 ]
机构：
[1] Univ Erlangen Nurnberg, Dept Biol, Div Genet, Erlangen, Germany
来源：
NATURE CANCER | 2022年 / 3卷 / 03期
关键词：
ANTI-CD40; ANTIBODIES;
D O I：
10.1038/s43018-022-00340-x
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Severe side effects limit the therapeutic potential of checkpoint control and immunomodulatory antibodies in immunotherapy of cancer. A new study demonstrates that bispecific antibodies directing the immunostimulatory activity of CD40-specific antibodies on dendritic cell subsets may allow a greater therapeutic window of opportunity.
引用
收藏
页码：268 / 269
页数：2
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