Successful Treatment of Cryptococcus laurentii Peritonitis in a Patient on Peritoneal Dialysis

被引：9
|
作者：
Asano, Marina [1 ]
Mizutani, Makoto [1 ]
Nagahara, Yasuko [1 ]
Inagaki, Koji [1 ]
Kariya, Tetsuyoshi [1 ]
Masamoto, Daijiro [1 ]
Urai, Makoto [2 ]
Kaneko, Yukihiro [2 ,3 ]
Ohno, Hideaki [2 ]
Miyazaki, Yoshitsugu [2 ]
Mizuno, Masashi [4 ]
Ito, Yasuhiko [4 ]
机构：
[1] Handa Municipal Hosp, Dept Nephrol, Handa, Japan
[2] Natl Inst Infect Dis, Dept Chemotherapy & Mycoses, Tokyo, Japan
[3] Osaka City Univ, Grad Sch Med, Dept Bacteriol, Osaka, Japan
[4] Nagoya Univ, Grad Sch Med, Dept Nephrol & Renal Replacement Therapy, Nagoya, Aichi 4648601, Japan
来源：
INTERNAL MEDICINE | 2015年 / 54卷 / 08期
关键词：
Cryptococcus laurentii; peritoneal dialysis; voriconazole; catheter removal; FUNGAL PERITONITIS; SINGLE; VORICONAZOLE; FLUCONAZOLE; INFECTIONS; FUNGEMIA;
D O I：
10.2169/internalmedicine.54.3586
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 32-year-old man on peritoneal dialysis (PD) was hospitalized for seven days due to fever. A diagnosis of yeast-like fungal peritonitis was made by Gram staining. The patient was started on intravenous micafungin and oral fluconazole therapy following removal of the PD catheter. A fungal pathogen was isolated from the peritoneal fluid and identified as Cryptococcus species. Based on antifungal susceptibility testing, the treatment was changed to voriconazole and continued for 3 months. A genetic analysis identified the isolate as Cryptococcus laurentii (C. laurentii). This patient was diagnosed with C. laurentii PD-related peritonitis and was successfully treated with voriconazole and removal of the PD catheter.
引用
收藏
页码：941 / 944
页数：4
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