Successful Treatment of Cryptococcus laurentii Peritonitis in a Patient on Peritoneal Dialysis

被引：10

作者：

Asano, Marina ^{[1
]}

Mizutani, Makoto ^{[1
]}

Nagahara, Yasuko ^{[1
]}

Inagaki, Koji ^{[1
]}

Kariya, Tetsuyoshi ^{[1
]}

Masamoto, Daijiro ^{[1
]}

Urai, Makoto ^{[2
]}

Kaneko, Yukihiro ^{[2
,3
]}

Ohno, Hideaki ^{[2
]}

Miyazaki, Yoshitsugu ^{[2
]}

Mizuno, Masashi ^{[4
]}

Ito, Yasuhiko ^{[4
]}

机构：

[1] Handa Municipal Hosp, Dept Nephrol, Handa, Japan

[2] Natl Inst Infect Dis, Dept Chemotherapy & Mycoses, Tokyo, Japan

[3] Osaka City Univ, Grad Sch Med, Dept Bacteriol, Osaka, Japan

[4] Nagoya Univ, Grad Sch Med, Dept Nephrol & Renal Replacement Therapy, Nagoya, Aichi 4648601, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 08期

关键词：

Cryptococcus laurentii; peritoneal dialysis; voriconazole; catheter removal; FUNGAL PERITONITIS; SINGLE; VORICONAZOLE; FLUCONAZOLE; INFECTIONS; FUNGEMIA;

D O I：

10.2169/internalmedicine.54.3586

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 32-year-old man on peritoneal dialysis (PD) was hospitalized for seven days due to fever. A diagnosis of yeast-like fungal peritonitis was made by Gram staining. The patient was started on intravenous micafungin and oral fluconazole therapy following removal of the PD catheter. A fungal pathogen was isolated from the peritoneal fluid and identified as Cryptococcus species. Based on antifungal susceptibility testing, the treatment was changed to voriconazole and continued for 3 months. A genetic analysis identified the isolate as Cryptococcus laurentii (C. laurentii). This patient was diagnosed with C. laurentii PD-related peritonitis and was successfully treated with voriconazole and removal of the PD catheter.

引用

页码：941 / 944

页数：4

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