Functional crosslinked polymer particles synthesized by precipitation polymerization for liquid chromatography

被引：44
作者：
Perrier-Cornet, R. [1 ]
Heroguez, V. [1 ]
Thienpont, A. [2 ]
Babot, O. [3 ]
Toupance, T. [3 ]
机构：
[1] Univ Bordeaux 1, CNRS, Lab Chim Polymeres Organ, F-33607 Pessac, France
[2] Univ Bordeaux 1, CNRS, Grp Nano Syst Anal, ISM, F-33607 Pessac, France
[3] Univ Bordeaux 1, CNRS, Grp Mat, ISM, F-33405 Pessac, France
来源：
JOURNAL OF CHROMATOGRAPHY A | 2008年 / 1179卷 / 01期
关键词：
polymer stationary phases; precipitation polymerization; liquid chromatography; functional crosslinked particles; porous particles;
D O I：
10.1016/j.chroma.2007.09.064
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Highly crosslinked functional polymer particles with narrow size distribution have been produced by precipitation copolymerization of divinylbenzene, ethylene glycol dimethacrylate and vinylbenzyl chloride using a simple reflux protocol. After establishing the satisfactory synthesis conditions, we produced uniform chlorobenzyl particles with different size depending on the polymerization times. The porosity of those particles was modulated from microporous to mesoporous structure by using various porogens such as toluene, dodecanol, cyclohexanol and polypropylene glycol. These particles were tested as stationary phase in high-performance liquid chromatography for the separation of polycyclic aromatic hydrocarbons in reversed-phase mode. The separation was observed even for elution 100% organic (methanol) without any participation of water fraction in the eluent composition. The influences of particles size, specific surface area and packing conditions on the separation behavior were investigated. (c) 2007 Elsevier B.V. All rights reserved.
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收藏
页码：2 / 8
页数：7
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