Anion transport across varying lipid membranes - the effect of lipophilicity

被引：46
作者：
Spooner, Michael J. [1 ]
Gale, Philip A. [1 ]
机构：
[1] Univ Southampton, Chem, Southampton SO17 1BJ, Hants, England
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 23期
基金：
英国工程与自然科学研究理事会;
关键词：
CHLORIDE TRANSPORT; CHOLESTEROL; RECEPTORS; HYDRATION; CARRIERS; DESIGN;
D O I：
10.1039/c5cc00823a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The anion transport properties of a range of alkyl-substituted phenylthioureas were tested in vesicles of different lipid composition. Although changes in the bilayer affected the rate of transport for all compounds in the series, the 'ideal' log P for peak activity did not change depending on the composition of the bilayers tested.
引用
收藏
页码：4883 / 4886
页数：4
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