Ixekizumab in Non-Radiographic Axial Spondyloarthritis: Primary Results from a Phase 3 Trial

被引：0

作者：

Deodhar, Atul ^{[1
]}

van der Heijde, Desiree ^{[2
]}

Gensler, Lianne ^{[3
]}

Kim, Tae-Hwan ^{[4
]}

Maksymowych, Walter P. ^{[5
]}

Ostergaard, Mikkel ^{[6
]}

Poddubnyy, Denis ^{[7
,8
]}

Marzo-Ortega, Helena ^{[9
]}

Bessette, Louis ^{[10
]}

Tomita, Tetsuya ^{[11
]}

Gallo, Gaia ^{[12
]}

Adams, David ^{[12
]}

Leung, Ann ^{[13
]}

Zhao, Fangyi ^{[12
]}

Hojnik, Maja ^{[12
]}

Carlier, Hilde ^{[12
]}

Sieper, Joachim ^{[7
]}

机构：

[1] Oregon Hlth & Sci Univ, Portland, OR 97201 USA

[2] Leiden Univ, Med Ctr, Leiden, Netherlands

[3] Univ Calif San Francisco, San Francisco, CA 94143 USA

[4] Hanyang Univ, Hosp Rheumat Dis, Seoul, South Korea

[5] Univ Alberta, Edmonton, AB, Canada

[6] Univ Copenhagen, Copenhagen Ctr Arthrit Res, Copenhagen, Denmark

[7] Charite Univ Med Berlin, Berlin, Germany

[8] German Rheumatism Res Ctr, Berlin, Germany

[9] Univ Leeds, Leeds Teaching Hosp NHS Trust, NIHR Leeds Biomed Res Ctr, Leeds, W Yorkshire, England

[10] Laval Univ, Quebec City, PQ, Canada

[11] Osaka Univ, Grad Sch Med, Osaka, Japan

[12] Eli Lilly & Co, Indianapolis, IN 46285 USA

[13] Syneos Hlth, Raleigh, NC USA

来源：

ARTHRITIS & RHEUMATOLOGY | 2019年 / 71卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2729

引用

页数：5

共 2 条

[1] Efficacy and Safety of Ixekizumab in the Treatment of Radiographic Axial Spondyloarthritis: Sixteen-Week Results From a Phase III Randomized, Double-Blind, Placebo-Controlled Trial in Patients With Prior Inadequate Response to or Intolerance of Tumor Necrosis Factor Inhibitors [J].

Deodhar, Atul ;

Poddubnyy, Denis ;

Pacheco-Tena, Cesar ;

Salvarani, Carlo ;

Lespessailles, Eric ;

Rahman, Proton ;

Jarvinen, Pentti ;

Sanchez-Burson, Juan ;

Gaffney, Karl ;

Lee, Eun Bong ;

Krishnan, Eswar ;

Santisteban, Silvia ;

Li, Xiaoqi ;

Zhao, Fangyi ;

Carlier, Hilde ;

Reveille, John D. ;

Antolini, Christopher ;

Azevedo, Valderilio ;

Barkham, Magnus ;

Rodriguez, Aaron Alejandro Barrera ;

Berman, Alberto ;

Blicharski, Tomasz ;

Brzezicki, Jan ;

Burmester, Gerd ;

Carrio, Judith ;

Collantes, Eduardo ;

Combe, Bernard ;

Cons-Molina, Fidencio ;

Cortes-Maisonet, Gregorio ;

Dudek, Anna ;

Barragan, Sergio Duran ;

Elkayam, Ori ;

Flint, Kathleen ;

Galeazzi, Mauro ;

Gaylis, Norman ;

Goddard, David ;

Fernandez, Carlos Gonzalez ;

Goupille, Philippe ;

Masmitja, Jordi Gratacos ;

Greenwald, Maria ;

Gremese, Elisa ;

Hong, Seung Jae ;

Howell, Mary ;

Hrycaj, Pawel ;

Ince, Akgun ;

Ju, Ji Hyeon ;

Kaine, Jeffrey ;

Kang, Seong Wook ;

Keiserman, Mauro ;

Kim, Tae-Hwan .

ARTHRITIS & RHEUMATOLOGY, 2019, 71 (04) :599-611

[2] Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological diseasemodifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial [J].

van der Heijde, Desiree ;

Wei, James Cheng-Chung ;

Dougados, Maxime ;

Mease, Philip ;

Deodhar, Atul ;

Maksymowych, Walter P. ;

Van den Bosch, Filip ;

Sieper, Joachim ;

Tomita, Tetsuya ;

Landewe, Robert ;

Zhao, Fangyi ;

Krishnan, Eswar ;

Adams, David H. ;

Pangallo, Beth ;

Carlier, Hilde .

LANCET, 2018, 392 (10163) :2441-2451

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