Can the index of myocardial performance be used to detect acute cellular rejection after heart transplantation?

被引:11
作者
Burgess, MI
Bright-Thomas, RJ
Yonan, N
Ray, SG
机构
[1] NW Lung Ctr, Dept Cardiol, Manchester, Lancs, England
[2] Wythenshawe Hosp, Cardiopulm Transplant Unit, Manchester M23 9LT, Lancs, England
关键词
D O I
10.1016/S0002-9149(03)00634-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The index of myocardial performance (IMP), combining systolic and diastolic function, was measured in 50 orthotopic heart transplant recipients to determine if it could be used to detect acute rejection. It was calculated as the sum of the isovolumic contraction time (IVCT) and isovolumic relaxation time (IVRT) divided by the ejection time. Comparison of intrarecipient changes in Doppler intervals between rejection and nonrejection states demonstrated an increase in IVCT and decrease in IVRT during rejection with no significant change in the IMP. Rejection is likely to be best detected by assessing these parameters independently rather than by measuring the IMP. (C)2003 by Excerpta Medica, Inc.
引用
收藏
页码:308 / 311
页数:4
相关论文
共 12 条
[1]  
Billingham M E, 1990, J Heart Transplant, V9, P587
[2]   ECHOCARDIOGRAPHIC ASSESSMENT OF CARDIAC ALLOGRAFT-REJECTION [J].
CILIBERTO, GR ;
CATALDO, G ;
CIPRIANI, M ;
MASCARELLO, M ;
FALETRA, F ;
GRONDA, E ;
DEMARIA, R ;
MAURI, L ;
PEZZANO, A .
EUROPEAN HEART JOURNAL, 1989, 10 (05) :400-408
[3]   DOPPLER ECHOCARDIOGRAPHY FOR THE DIAGNOSIS OF ACUTE CARDIAC ALLOGRAFT-REJECTION [J].
DESRUENNES, M ;
CORCOS, T ;
CABROL, A ;
GANDJBAKHCH, I ;
PAVIE, A ;
LEGER, P ;
EUGENE, M ;
BORS, V ;
CABROL, C .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1988, 12 (01) :63-70
[4]  
FORSTER T, 1988, J HEART TRANSPLANT, V7, P430
[5]   ECHOCARDIOGRAPHIC DIAGNOSIS OF CARDIAC ALLOGRAFT-REJECTION [J].
HSU, DT ;
SPOTNITZ, HM .
PROGRESS IN CARDIOVASCULAR DISEASES, 1990, 33 (03) :149-160
[7]   Differences in heart transplant physiology according to surgical technique [J].
Peteiro, J ;
Redondo, F ;
Calvino, R ;
Cuenca, J ;
Pradas, G ;
Beiras, AC .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1996, 112 (03) :584-589
[8]  
STINSON EB, 1974, J THORAC CARDIOV SUR, V68, P783
[9]  
Tei C, 1995, J Cardiol, V26, P357
[10]  
VALANTINE HA, 1987, CIRCULATION, V76, P86