Interaction profiling of T-cell epitopes with MHC-Class I molecules

被引：0
作者：
Dash, Banaja Priyardarshini
Mukherjee, Sumanto
Suhas, V. L.
Chandra, Nagasuma
机构：
[1] Indian Inst Sci, Bioinformat Ctr, Bangalore 560012, Karnataka, India
[2] Indian Inst Sci, SERC, Bangalore 560012, Karnataka, India
来源：
PROTEIN AND PEPTIDE LETTERS | 2007年 / 14卷 / 06期
关键词：
epitope prediction; protein-peptide interaction; HLA class-I; vaccine design; structural bioinformatics;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A key step in rational vaccine development is to understand how antigens are recognized by their receptors. Several crystal structures of MHC/HLA molecules are now available. We report a structural bioinformatics study of peptide-HLA complexes to derive features that generate recognition specificity, useful for guiding the design process.
引用
收藏
页码：557 / 564
页数：8
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