Sarcopenia and Frailty in Elderly: Manifestations, Impacts on Diseases, and Management

被引:4
作者
Chao, Wen-Chi [1 ]
Wang, Shen-Yung [2 ]
机构
[1] MacKay Mem Hosp, Dept Crit Care Med, Taipei, Taiwan
[2] MacKay Mem Hosp, Dept Med, Div Gastroenterol & Hepatol, Taipei, Taiwan
关键词
frailty; sarcopenia; elderly; DIETARY-PROTEIN INTAKE; SKELETAL-MUSCLE; OLDER-ADULTS; DOUBLE-BLIND; VITAMIN-D; COMPUTED-TOMOGRAPHY; QUADRICEPS MUSCLE; BODY-COMPOSITION; HEART-FAILURE; MASS;
D O I
10.6890/IJGE.202002_14(1).0001
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aging population is frequently associated with a progressive function decline. Sarcopenia and frailty are common in elderly. Sarcopenia, defined by loss of muscle mass and strength and function, is a crucial driver for frailty. Sarcopenia can result from aging process, malnutrition, inactivity, and chronic diseases. Sarcopenia is highly prevalent in frail individuals. Frailty is a geriatric syndrome connected to adverse clinical outcomes. Frailty is associated with disability or increased mortality in elderly. Sarcopenia and frailty are prevalent in various diseases such as heart failure, chronic kidney disease, chronic obstructive pulmonary disease, and critical illness. Adequate nutritional support with higher protein ingestion in addition to exercise are crucial to improve physical performance in sarcopenic or frail elderly. Copyright (C) 2020, Taiwan Society of Geriatric Emergency & Critical Care Medicine.
引用
收藏
页码:2 / 5
页数:4
相关论文
共 61 条
  • [1] Wasting as independent risk factor for mortality in chronic heart failure
    Anker, SD
    Ponikowski, P
    Varney, S
    Chua, TP
    Clark, AL
    WebbPeploe, KM
    Harrington, D
    Kox, WJ
    PooleWilson, PA
    Coats, AJS
    [J]. LANCET, 1997, 349 (9058) : 1050 - 1053
  • [2] Association between frailty and short- and long-term outcomes among critically ill patients: a multicentre prospective cohort study
    Bagshaw, Sean M.
    Stelfox, H. Thomas
    McDermid, Robert C.
    Rolfson, Darryl B.
    Tsuyuki, Ross T.
    Baig, Nadia
    Artiuch, Barbara
    Ibrahim, Quazi
    Stollery, Daniel E.
    Rokosh, Ella
    Majumdar, Sumit R.
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2014, 186 (02) : E95 - E102
  • [3] Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group
    Bauer, Juergen
    Biolo, Gianni
    Cederholm, Tommy
    Cesari, Matteo
    Cruz-Jentoft, Alfonso J.
    Morley, John E.
    Phillips, Stuart
    Sieber, Cornel
    Stehle, Peter
    Teta, Daniel
    Visvanathan, Renuka
    Volpi, Elena
    Boirie, Yves
    [J]. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2013, 14 (08) : 542 - 559
  • [4] Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double-Blind, Placebo-Controlled Trial
    Bauer, Juergen M.
    Verlaan, Sjors
    Bautmans, Ivan
    Brandt, Kirsten
    Donini, Lorenzo M.
    Maggio, Marcello
    McMurdo, Marion E. T.
    Mets, Tony
    Seal, Chris
    Wijers, Sander L.
    Ceda, Gian Paolo
    De Vito, Giuseppe
    Donders, Gilbert
    Drey, Michael
    Greig, Carolyn
    Holmback, Ulf
    Narici, Marco
    McPhee, Jamie
    Poggiogalle, Eleonora
    Power, Dermot
    Scafoglieri, Aldo
    Schultz, Ralf
    Sieber, Cornel C.
    Cederholm, Tommy
    [J]. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2015, 16 (09) : 740 - 747
  • [5] Vitamin D receptor expression in human muscle tissue decreases with age
    Bischoff-Ferrari, HA
    Borchers, M
    Gudat, F
    Dürmüller, U
    Stähelin, HB
    Dick, W
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2004, 19 (02) : 265 - 269
  • [6] A frailty index derived from a standardized comprehensive geriatric assessment predicts mortality and aged residential care admission
    Burn, Rosie
    Hubbard, Ruth E.
    Scrase, Richard J.
    Abey-Nesbit, Rebecca K.
    Peel, Nancye M.
    Schluter, Philip J.
    Jamieson, Hamish A.
    [J]. BMC GERIATRICS, 2018, 18
  • [7] A Randomized Study on the Effect of Vitamin D3 Supplementation on Skeletal Muscle Morphology and Vitamin D Receptor Concentration in Older Women
    Ceglia, Lisa
    Niramitmahapanya, Sathit
    Morais, Mauricio da Silva
    Rivas, Donato A.
    Harris, Susan S.
    Bischoff-Ferrari, Heike
    Fielding, Roger A.
    Dawson-Hughes, Bess
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (12) : E1927 - E1935
  • [8] Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis
    Cermak, Naomi M.
    Res, Peter T.
    de Groot, Lisette C. P. G. M.
    Saris, Wim H. M.
    van Loon, Luc J. C.
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2012, 96 (06) : 1454 - 1464
  • [9] Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study
    Cesari, M
    Leeuwenburgh, C
    Lauretani, F
    Onder, G
    Bandinelli, S
    Maraldi, C
    Guralnik, JM
    Pahor, M
    Ferrucci, L
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 83 (05) : 1142 - 1148
  • [10] Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia
    Chen, Liang-Kung
    Liu, Li-Kuo
    Woo, Jean
    Assantachai, Prasert
    Auyeung, Tung-Wai
    Bahyah, Kamaruzzaman Shahrul
    Chou, Ming-Yueh
    Chen, Liang-Yu
    Hsu, Pi-Shan
    Krairit, Orapitchaya
    Lee, Jenny S. W.
    Lee, Wei-Ju
    Lee, Yunhwan
    Liang, Chih-Kuang
    Limpawattana, Panita
    Lin, Chu-Sheng
    Peng, Li-Ning
    Satake, Shosuke
    Suzuki, Takao
    Won, Chang Won
    Wu, Chih-Hsing
    Wu, Si-Nan
    Zhang, Teimei
    Zeng, Ping
    Akishita, Masahiro
    Arai, Hidenori
    [J]. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2014, 15 (02) : 95 - 101