Limb preserving surgery for soft-tissue sarcoma in the hand: a retrospective study of 51 cases

被引:4
作者
Dadras, Mehran [1 ]
Steinau, Hans-Ulrich [1 ,2 ]
Goertz, Ole [1 ,3 ]
Lehnhardt, Marcus [1 ]
Behr, Bjoern [1 ]
Harati, Kamran [1 ]
机构
[1] BG Univ Hosp Bergmannsheil, Dept Plast Surg & Hand Surg, Burkle Camp Pl 1, D-44789 Bochum, Germany
[2] Univ Essen Gesamthsch, Univ Clin Essen, Tumor Ctr West Germany, Sarcoma Ctr, Essen, Germany
[3] Martin Luther Hosp, Dept Plast Reconstruct & Aesthet Surg, Berlin, Germany
关键词
Sarcoma; tumour; amputation; soft tissue sarcoma; RADIATION-THERAPY; PROGNOSTIC-SIGNIFICANCE; SURGICAL MARGINS; LOCAL RECURRENCE; EXTREMITIES; CLASSIFICATION; IMPACT; TUMOR;
D O I
10.1177/1753193419899037
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Our retrospective study analysed the long-term results of a conservative limb-preserving surgical strategy in 51 patients with soft-tissue sarcoma of the hand from a single institution. We assessed survival and prognostic factors, including the surgical margins. No transradial amputations were performed. Microscopically free resection margins were obtained in 45 of the patients. The remaining six patients had microscopically incomplete resection. Forty-four surviving patients had a median follow-up of 6.5 years (range 12-307), and one patient had no follow-up beyond 3 months following surgery. Among those patients, 29 had more than 5 years of follow-up. Five-year local-recurrence-free survival was 65%, metastasis-free survival was 84%, and disease-specific survival was 91%. Tumour size was predictive of all outcome parameters, but positive resection margins adversely affected local recurrence only. Survival was similar to the survival after a more radical surgical approach reported in the literature.
引用
收藏
页码:629 / 635
页数:7
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