Limb preserving surgery for soft-tissue sarcoma in the hand: a retrospective study of 51 cases

被引:4
作者
Dadras, Mehran [1 ]
Steinau, Hans-Ulrich [1 ,2 ]
Goertz, Ole [1 ,3 ]
Lehnhardt, Marcus [1 ]
Behr, Bjoern [1 ]
Harati, Kamran [1 ]
机构
[1] BG Univ Hosp Bergmannsheil, Dept Plast Surg & Hand Surg, Burkle Camp Pl 1, D-44789 Bochum, Germany
[2] Univ Essen Gesamthsch, Univ Clin Essen, Tumor Ctr West Germany, Sarcoma Ctr, Essen, Germany
[3] Martin Luther Hosp, Dept Plast Reconstruct & Aesthet Surg, Berlin, Germany
关键词
Sarcoma; tumour; amputation; soft tissue sarcoma; RADIATION-THERAPY; PROGNOSTIC-SIGNIFICANCE; SURGICAL MARGINS; LOCAL RECURRENCE; EXTREMITIES; CLASSIFICATION; IMPACT; TUMOR;
D O I
10.1177/1753193419899037
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Our retrospective study analysed the long-term results of a conservative limb-preserving surgical strategy in 51 patients with soft-tissue sarcoma of the hand from a single institution. We assessed survival and prognostic factors, including the surgical margins. No transradial amputations were performed. Microscopically free resection margins were obtained in 45 of the patients. The remaining six patients had microscopically incomplete resection. Forty-four surviving patients had a median follow-up of 6.5 years (range 12-307), and one patient had no follow-up beyond 3 months following surgery. Among those patients, 29 had more than 5 years of follow-up. Five-year local-recurrence-free survival was 65%, metastasis-free survival was 84%, and disease-specific survival was 91%. Tumour size was predictive of all outcome parameters, but positive resection margins adversely affected local recurrence only. Survival was similar to the survival after a more radical surgical approach reported in the literature.
引用
收藏
页码:629 / 635
页数:7
相关论文
共 26 条
  • [1] Classification of surgical complications - A new proposal with evaluation in a cohort of 6336 patients and results of a survey
    Dindo, D
    Demartines, N
    Clavien, PA
    [J]. ANNALS OF SURGERY, 2004, 240 (02) : 205 - 213
  • [2] ENNEKING WF, 1981, CANCER-AM CANCER SOC, V47, P1005, DOI 10.1002/1097-0142(19810301)47:5<1005::AID-CNCR2820470532>3.0.CO
  • [3] 2-9
  • [4] Extremity Soft Tissue Sarcoma in a Series of Patients Treated at a Single Institution Local Control Directly Impacts Survival
    Gronchi, Alessandro
    Lo Vullo, Salvatore
    Colombo, Chiara
    Collini, Paola
    Stacchiotti, Silvia
    Mariani, Luigi
    Fiore, Marco
    Casali, Paolo Giovanni
    [J]. ANNALS OF SURGERY, 2010, 251 (03) : 506 - 511
  • [5] Analysis of Margin Classification Systems for Assessing the Risk of Local Recurrence After Soft Tissue Sarcoma Resection
    Gundle, Kenneth R.
    Kafchinski, Lisa
    Gupta, Sanjay
    Griffin, Anthony M.
    Dickson, Brendan C.
    Chung, Peter W.
    Catton, Charles N.
    O'Sullivan, Brian
    Wunder, Jay S.
    Ferguson, Peter C.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (07) : 704 - +
  • [6] Harati K, 2017, INNOV SURG SCI, V2, P165, DOI 10.1515/iss-2017-0043
  • [7] Soft Tissue Sarcomas of the Extremities: Surgical Margins Can Be Close as Long as the Resected Tumor Has No Ink on It
    Harati, Kamran
    Goertz, Ole
    Pieper, Andreas
    Daigeler, Adrien
    Joneidi-Jafari, Hamid
    Niggemann, Hiltrud
    Stricker, Ingo
    Lehnhardt, Marcus
    [J]. ONCOLOGIST, 2017, 22 (11) : 1400 - 1410
  • [8] Soft tissue sarcomas of the distal lower extremities: A single-institutional analysis of the prognostic significance of surgical margins in 120 patients
    Harati, Kamran
    Kirchhoff, Pascal
    Behr, Bjoern
    Daigeler, Adrien
    Goertz, Ole
    Hirsch, Tobias
    Lehnhardt, Marcus
    Ring, Andrej
    [J]. ONCOLOGY REPORTS, 2016, 36 (02) : 863 - 870
  • [9] Houdek Matthew T, 2017, Hand (N Y), V12, P493, DOI 10.1177/1558944716672197
  • [10] Oncological outcome of primary non-metastatic soft tissue sarcoma treated by neoadjuvant isolated limb perfusion and tumor resection
    Jakob, Jens
    Tunn, Per-Ulf
    Hayes, Andrew J.
    Pilz, Lothar R.
    Nowak, Kai
    Hohenberger, Peter
    [J]. JOURNAL OF SURGICAL ONCOLOGY, 2014, 109 (08) : 786 - 790