Carvacrol and thymol components inhibiting Pseudomonas aeruginosa adherence and biofilm formation

被引：1

作者：

Soumya, El Abed ^{[1
,2
]}

Saad, Ibnsouda Koraichi ^{[1
,2
]}

Hassan, Latrache ^{[3
]}

Ghizlane, Zineb ^{[1
]}

Hind, Mouradi ^{[1
]}

Adnane, Remmal ^{[4
]}

机构：

[1] Fac Sci & Tech Fes Sais, Lab Biotechnol Microbienne, Fes, Morocco

[2] Univ Sidi Mohamed Ben Abdellah Fes, Ctr Univ Reg Interface, Fes, Morocco

[3] Fac Sci & Tech BeniMellal, Lab Valorisat & Securite Prod Agroalimentaires, Beni Mellal, Morocco

[4] Fac Sci Dhar El Mehraz Fes, Biotechnol Lab, Fes, Morocco

来源：

AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH | 2011年 / 5卷 / 20期

关键词：

Biofilm; adherence; carvacrol; thymol; Pseudomonas aeruginosa; OREGANO ESSENTIAL OIL; ANTIFUNGAL ACTIVITIES; SUSCEPTIBILITY; MICROORGANISMS; MECHANISMS; RESISTANCE;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Pseudomonas aeruginosa has a high propensity to develop biofilms that are resistant to exogenous deleterious agents. The aim of this study was to investigate whether carvacrol and thymol can interfere with adherence phenomena as well as acting on biofilm formation. Tests of P. aeruginosa strains showed that carvacrol and thymol interferes with the starting phases of adherence as well as with P. aeruginosa biofilms. Carvacrol and thymol (2MIC) inhibition was 97 +/- 8.5 and 89 +/- 6.3% for P. aeruginosa (ATCC 27853) and 72 +/- 4.6 and 69 +/- 6.8% for P. aeruginosa (CIP A22) adherence respectively. Carvacrol (2MIC) inhibition exceeds 90% for P. aeruginosa (ATCC 27853) and P. aeruginosa (IL5) biofilm. Thymol (2MIC) inhibition is 86 +/- 2.1, 54 +/- 5.9 and 70 +/- 4.3% for P. aeruginosa (ATCC 27853) P. aeruginosa (CIP A22), P. aeruginosa (IL5), respectively.

引用

页码：3229 / 3232

页数：4

共 34 条

[1] Antifungal activities of Origanum vulgare subsp. hirtum, Mentha spicata, Lavandula angustifolia, and Salvia fruticosa essential oils against human pathogenic fungi [J].