Copper(i)-catalyzed intermolecular cyanoarylation of alkenes: convenient access to α-alkylated arylacetonitriles

被引：14

作者：

Chen, Xin-Jie ^{[1
]}

Gui, Qing-Wen ^{[3
]}

Yi, Rongnan ^{[2
]}

Yu, Xianyong ^{[1
]}

Wu, Zhi-Lin ^{[4
]}

Huang, Ying ^{[3
]}

Cao, Zhong ^{[3
]}

He, Wei-Min ^{[3
]}

机构：

[1] Hunan Univ Sci & Technol, Minist Educ, Sch Chem & Chem Engn, Key Lab Theoret Organ Chem & Funct Mol, Xiangtan 411201, Peoples R China

[2] Hunan Univ, Dept Chem, Changsha 410082, Hunan, Peoples R China

[3] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Rans, Changsha 410114, Peoples R China

[4] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2020年 / 18卷 / 27期

关键词：

DIARYLIODONIUM SALTS; CASCADE ANNULATION; REGIOSELECTIVE SYNTHESIS; ARYLATION; NITRILES; PHOTOREDOX; QUINOXALIN-2(1H)-ONES; ALCOHOLS; CYANOALKYLATION; ALKYLNITRILES;

D O I：

10.1039/d0ob01055c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel Cu(i)-catalyzed intermolecular cyanoarylation of alkenes with diaryliodonium salts as a radical arylating reagent andtetra-butylammonium cyanide as an electrophilic cyanating reagent was established. A broad range of alpha-alkylated arylacetonitriles were efficiently constructed in good to excellent yields under base- and oxidant-free and mild conditions.

引用

页码：5234 / 5237

页数：4

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