Role of Saliva and Salivary Diagnostics in the Advancement of Oral Health

被引：130

作者：

Dawes, C. ^{[1
]}

Wong, D. T. W. ^{[2
]}

机构：

[1] Univ Manitoba, Dept Oral Biol, Coll Dent, Winnipeg, MB, Canada

[2] Univ Calif Los Angeles, Sch Dent, Div Oral Biol & Med, Ctr Oral Head & Neck Oncol Res, 10833 Le Conte Ave,CHS 73-017, Los Angeles, CA 90095 USA

来源：

JOURNAL OF DENTAL RESEARCH | 2019年 / 98卷 / 02期

关键词：

parotid; submandibular/sublingual; exosomics; proteomics; salivaomics; transcriptomics; PANCREATIC EXOCRINE CELL; CIRCULATING TUMOR-CELLS; HUMAN-PAROTID SALIVA; INTRACELLULAR-TRANSPORT; MATHEMATICAL-MODEL; SECRETORY PROTEINS; MUTATION DETECTION; DENTAL-CARIES; RICH PROTEINS; LUNG-CANCER;

D O I：

10.1177/0022034518816961

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The objective of this article was to provide an account of some of the developments related to saliva over the first 100 years of the Journal of Dental Research and to outline some of the many biomarkers identified in saliva in the last few years. The first section covers findings in salivary physiology, biochemistry, calcium phosphate chemistry related to saliva, microbiology, and the role of saliva in maintaining oral health. The second section highlights salivary diagnostics, salivaomics, and saliva exosomics in the context of the emerging theme of personalized and precision medicine.

引用

页码：133 / 141

页数：9

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