Synthesis and characterization of chlorodiphenylgermanium dithiocarbamates

被引:0
|
作者
Yin, HD [1 ]
Zhang, RF [1 ]
Wang, Y [1 ]
Ma, CL [1 ]
Lei, FQ [1 ]
机构
[1] Liaocheng Teachers Univ, Dept Chem, Liaoceng 252059, Peoples R China
关键词
diphenylgermanium; dithiocarbamate; synthesis; biological activity;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Thirteen chlorodiphenylgermanium dithiocarbamates Ph2GeCl(S2CNRR') Were synthesized by the reaction of corresponding diphenylgermanium dichloride with dithiocarbamates in 1:1 stoichiometry. Their structure were confirmed by elemental analysis, IR, 'HNMR and MS. These results revealed that the dithiocarbamate ligands were coordinated to Ge in an anisobidentate fashion. Preliminary study of their biological activity showed that some of them had better antitumour activity in vitro.
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页码:589 / 592
页数:4
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