Molecular Epidemiology of Clostridium difficile Strains in Children Compared with That of Strains Circulating in Adults with Clostridium difficile-Associated Infection

被引：31
|
作者：
Stoesser, Nicole [1 ,3 ]
Crook, Derrick W. [1 ,3 ]
Fung, Rowena [1 ,3 ]
Griffiths, David [1 ,3 ]
Harding, Rosalind M. [3 ,4 ]
Kachrimanidou, Melina [1 ,3 ]
Keshav, Satish [6 ]
Peto, Tim E. [1 ,3 ]
Vaughan, Alison [1 ,3 ]
Walker, A. Sarah [1 ,3 ,5 ]
Dingle, Kate E. [2 ,3 ]
机构：
[1] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England
[2] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Lab Sci, Oxford OX3 9DU, England
[3] John Radcliffe Hosp, Natl Inst Hlth Res, Oxford Biomed Res Ctr Program, Oxford OX3 9DU, England
[4] Univ Oxford, Dept Zool, Oxford OX1 3PS, England
[5] MRC Clin Trials Unit, London NW1 2DA, England
[6] John Radcliffe Hosp, Translat Gastroenterol Unit, Oxford OX3 9DU, England
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 11期
关键词：
TOXIN; COLONIZATION; OUTBREAKS; DIARRHEA; INFANTS; DISEASE;
D O I：
10.1128/JCM.05349-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.
引用
收藏
页码：3994 / 3996
页数：3
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