LKB1 Mutation Status is Associated with Poor Radiation Outcome in Patients with Non-Small Cell Lung Cancer

被引：0
|
作者：
Sitthideatphaiboon, P. [1 ]
Cobo, A. [2 ,3 ]
Poteete, A. [2 ,3 ]
Zhang, F. [2 ,3 ]
Lui, D. [4 ]
Rinsurongkawong, W. [5 ]
Heymach, J. [6 ]
机构：
[1] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Div Med Oncol, Dept Med,Fac Med, Bangkok, Thailand
[2] Univ Texas MD Anderson Canc Ctr, Dept Thorac Oncol, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Head & Neck Med Oncol, Houston, TX 77030 USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA
[5] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[6] Univ Texas MD Anderson Canc Ctr, Thorac Head & Neck Med Oncol, Houston, TX 77030 USA
来源：
JOURNAL OF THORACIC ONCOLOGY | 2018年 / 13卷 / 10期
关键词：
Liver Kinase B1; Kelch-like ECH-Associated Protein 1; Radio-resistance;
D O I：
10.1016/j.jtho.2018.08.1705
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P3.03-28
引用
收藏
页码：S921 / S921
页数：1
相关论文
共 50 条
  • [21] LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab
    Bonanno, Laura
    De Paoli, Angela
    Zulato, Elisabetta
    Esposito, Giovanni
    Calabrese, Fiorella
    Favaretto, Adolfo
    Santo, Antonio
    Del Conte, Alessandro
    Chilosi, Marco
    Oniga, Francesco
    Sozzi, Gabriella
    Moro, Massimo
    Ciccarese, Francesco
    Nardo, Giorgia
    Bertorelle, Roberta
    Candiotto, Cinzia
    De Salvo, Gian Luca
    Amadori, Alberto
    Conte, PierFranco
    Indraccolo, Stefano
    CLINICAL CANCER RESEARCH, 2017, 23 (13) : 3316 - 3324
  • [22] LKB1 Loss Correlates with STING Loss and, in Cooperation with β-Catenin Membranous Loss, Indicates Poor Prognosis in Patients with Operable Non-Small Cell Lung Cancer
    Lagoudaki, Eleni D.
    Koutsopoulos, Anastasios V.
    Sfakianaki, Maria
    Papadaki, Chara
    Manikis, Georgios C.
    Voutsina, Alexandra
    Trypaki, Maria
    Tsakalaki, Eleftheria
    Fiolitaki, Georgia
    Hatzidaki, Dora
    Yiachnakis, Emmanuel
    Koumaki, Dimitra
    Mavroudis, Dimitrios
    Tzardi, Maria
    Stathopoulos, Efstathios N.
    Marias, Kostas
    Georgoulias, Vassilis
    Souglakos, John
    CANCERS, 2024, 16 (10)
  • [23] Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status
    Granja, Sara
    Marchiq, Ibtissam
    Le Floch, Renaud
    Moura, Conceicao Souto
    Baltazar, Fatima
    Pouyssegur, Jacques
    ONCOTARGET, 2015, 6 (09) : 6708 - 6721
  • [24] Phenformin enhances the therapeutic effect of selumetinib in KRAS-mutant non-small cell lung cancer irrespective of LKB1 status
    Zhang, Jun
    Nannapaneni, Sreenivas
    Wang, Dongsheng
    Liu, Fakeng
    Wang, Xu
    Jin, Rui
    Liu, Xiuju
    Rahman, Mohammad Aminur
    Peng, Xianghong
    Qian, Guoqing
    Chen, Zhuo G.
    Wong, Kwok-Kin
    Khuri, Fadlo R.
    Zhou, Wei
    Shin, Dong M.
    ONCOTARGET, 2017, 8 (35) : 59008 - 59022
  • [25] High expression of FOXC1 is associated with poor clinical outcome in non-small cell lung cancer patients
    Wei, Long-Xiao
    Zhou, Run-Suo
    Xu, Hai-Feng
    Wang, Jun-Yan
    Yuan, Meng-Hui
    TUMOR BIOLOGY, 2013, 34 (02) : 941 - 946
  • [26] LKB1/AMPK/TSC2 signaling pathway alterations in non-small cell lung cancer
    De Aguirre, I
    Zhong, D
    Zhou, W
    Rosell, R
    Vertino, P
    LUNG CANCER, 2005, 49 : S69 - S69
  • [27] LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin
    Shackelford, David B.
    Abt, Evan
    Gerken, Laurie
    Vasquez, Debbie S.
    Seki, Atsuko
    Leblanc, Mathias
    Wei, Liu
    Fishbein, Michael C.
    Czernin, Johannes
    Mischel, Paul S.
    Shaw, Reuben J.
    CANCER CELL, 2013, 23 (02) : 143 - 158
  • [28] LKB1 Mutations in Metastatic Non-Small Cell Lung Cancer (mNSCLC): Prognostic Value in the Real World
    Golozar, A.
    Collins, J.
    Fraeman, K.
    Nordstrom, B.
    Mcewen, R.
    Shire, N.
    Higgs, B.
    JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S223 - S224
  • [29] Mutations of the LKB1/STK11 gene in non-small cell lung cancer with loss of heterozygosity
    Yang, Sei-Hoon
    Meerzaman, Daoud
    Mechanic, Leah E.
    Gill, Rajbir
    Dracheva, Tatiana
    Han, Seung-Bum
    Kim, Sam-Yong
    Bowman, Elise D.
    Harris, Curtis C.
    Jen, Jin
    ANNALS OF ONCOLOGY, 2006, 17 : 246 - 246
  • [30] Frequent homozygous deletion of the LKB1/STK11 gene in non-small cell lung cancer
    R K Gill
    S-H Yang
    D Meerzaman
    L E Mechanic
    E D Bowman
    H-S Jeon
    S Roy Chowdhuri
    A Shakoori
    T Dracheva
    K-M Hong
    J Fukuoka
    J-H Zhang
    C C Harris
    J Jen
    Oncogene, 2011, 30 : 3784 - 3791
12345